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    cid12 poly(A) polymerase Cid12 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539423, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cid12
    Official Full Name
    poly(A) polymerase Cid12
    Primary source
    PomBase:SPCC663.12
    Locus tag
    SPOM_SPCC663.12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    csp10; csp8
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    Genomic context

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    See cid12 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (1655646..1660080)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene splicing-associated factor Saf1 Neighboring gene NatA N-acetyltransferase subunit Naa50 Neighboring gene TRP-like ion channel protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene oxidoreductase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The intron in centromeric noncoding RNA facilitates RNAi-mediated formation of heterochromatin. Mutazono M, et al. PLoS Genet, 2017 Feb. PMID 28231281, Free PMC Article
    2. Distinct roles for Sir2 and RNAi in centromeric heterochromatin nucleation, spreading and maintenance. Buscaino A, et al. EMBO J, 2013 May 2. PMID 23572080, Free PMC Article
    3. Dicer-independent primal RNAs trigger RNAi and heterochromatin formation. Halic M, et al. Cell, 2010 Feb 19. PMID 20178743, Free PMC Article
    4. Splicing factors facilitate RNAi-directed silencing in fission yeast. Bayne EH, et al. Science, 2008 Oct 24. PMID 18948543, Free PMC Article
    5. Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Motamedi MR, et al. Cell, 2004 Dec 17. PMID 15607976

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cid12 has dual functions in RNAi silencing and regulating mRNA stability
      Title: Fission yeast Cid12 has dual functions in chromosome segregation and checkpoint control.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables poly(A) RNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables poly(A) RNA polymerase activity ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulatory ncRNA-mediated heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in siRNA-mediated pericentric heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA-directed RNA polymerase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    part_of nuclear RNA-directed RNA polymerase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    poly(A) polymerase Cid12

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1655646..1660080
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023263.3 → NP_588273.1  poly(A) polymerase Cid12 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588273.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74518
      Conserved Domains (3) summary
      cd05402
      Location:41 → 147
      NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases
      COG5260
      Location:1 → 336
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
      pfam03828
      Location:206 → 263
      PAP_assoc; Cid1 family poly A polymerase
    Nucleotide Protein
    Heading Accession and Version

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