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    trp1 anthranilate synthase component II [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539973, updated on 18-Sep-2024

    Summary

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    Official Symbol
    trp1
    Official Full Name
    anthranilate synthase component II
    Primary source
    PomBase:SPBC1539.09c
    Locus tag
    SPOM_SPBC1539.09C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See trp1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (4377221..4379581, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene glutathione-dependent formaldehyde dehydrogenase Neighboring gene ncRNA Neighboring gene ADP-ribosylation factor-like protein Arf6 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein Nop16

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Organisation of the complex locus trp1 in the fission yeast Schizosaccharomyces pombe. Thuriaux P, et al. Curr Genet, 1982 Oct. PMID 24186364
    2. Megadalton-node assembly by binding of Skb1 to the membrane anchor Slf1. Deng L, et al. Mol Biol Cell, 2014 Sep 1. PMID 25009287, Free PMC Article
    3. Caffeine-resistance in S. pombe: mutations in three novel caf genes increase caffeine tolerance and affect radiation sensitivity, fertility, and cell cycle. Benko Z, et al. Curr Genet, 1997 Jun. PMID 9211790
    4. Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions. Nie M, et al. J Biol Chem, 2012 Aug 24. PMID 22730331, Free PMC Article
    5. Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis. Snaith HA, et al. J Cell Sci, 2011 Jul 1. PMID 21652630, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables anthranilate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables indole-3-glycerol-phosphate synthase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables phosphoribosylanthranilate isomerase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in tryptophan biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tryptophan biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in tryptophan metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of anthranilate synthase complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    anthranilate synthase component II

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      4377221..4379581 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023843.2 → NP_596823.1  anthranilate synthase component II [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596823.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q92370, Q9UUF5
      Conserved Domains (5) summary
      COG0512
      Location:28 → 216
      PabA; Anthranilate/para-aminobenzoate synthase component II [Amino acid transport and metabolism, Coenzyme transport and metabolism]
      PRK05670
      Location:28 → 218
      PRK05670; anthranilate synthase component II; Provisional
      PRK09427
      Location:252 → 758
      PRK09427; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional
      cd00405
      Location:537 → 756
      PRAI; Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are monomeric, ...
      pfam00218
      Location:258 → 517
      IGPS; Indole-3-glycerol phosphate synthase
    Nucleotide Protein
    Heading Accession and Version

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