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    crs1 cyclin Crs1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540450, updated on 14-Nov-2024

    Summary

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    Official Symbol
    crs1
    Official Full Name
    cyclin Crs1
    Primary source
    PomBase:SPBC2G2.09c
    Locus tag
    SPOM_SPBC2G2.09C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mug17
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    Genomic context

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    See crs1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003423.3 (3452323..3453516, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial 37S ribosomal protein bS1m Neighboring gene trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase Neighboring gene ncRNA Neighboring gene protein mug110 Neighboring gene N-myristoyltransferase 1 Neighboring gene deoxycytidylate deaminase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Meiosis-Specific Crs1 Cyclin Is Required for Efficient S-Phase Progression and Stable Nuclear Architecture. Bustamante-Jaramillo LF, et al. Int J Mol Sci, 2021 May 22. PMID 34067465, Free PMC Article
    2. A complex gene regulatory mechanism that operates at the nexus of multiple RNA processing decisions. McPheeters DS, et al. Nat Struct Mol Biol, 2009 Mar. PMID 19198588, Free PMC Article
    3. CDK contribution to DSB formation and recombination in fission yeast meiosis. Bustamante-Jaramillo LF, et al. PLoS Genet, 2019 Jan. PMID 30640914, Free PMC Article
    4. Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy. Folco HD, et al. Nature, 2017 Mar 2. PMID 28199302, Free PMC Article
    5. A single cyclin-CDK complex is sufficient for both mitotic and meiotic progression in fission yeast. Gutiérrez-Escribano P, et al. Nat Commun, 2015 Apr 20. PMID 25891897, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase regulator activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G1/S transition of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of meiotic cell cycle phase transition NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in signaling NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    part_of cyclin-dependent protein kinase holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in meiotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleoplasm EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cyclin Crs1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3452323..3453516 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022357.4 → NP_596438.3  cyclin Crs1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596438.3

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O43008
      Conserved Domains (1) summary
      cl00050
      Location:105 → 182
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
    Nucleotide Protein
    Heading Accession and Version

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