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    hfi1 SAGA complex subunit Hfi1/Ada1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541202, updated on 18-Sep-2024

    Summary

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    Official Symbol
    hfi1
    Official Full Name
    SAGA complex subunit Hfi1/Ada1
    Primary source
    PomBase:SPBC887.18c
    Locus tag
    SPOM_SPBC887.18C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ada1
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    Genomic context

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    See hfi1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (3578033..3579719, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene transmembrane transporter Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Man5GlcNac2-PP-Dol translocation protein Rft1 Neighboring gene imidazoleglycerol-phosphate synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Whole-Genome Sequencing of Suppressor DNA Mixtures Identifies Pathways That Compensate for Chromosome Segregation Defects in Schizosaccharomyces pombe. Xu X, et al. G3 (Bethesda), 2018 Mar 2. PMID 29352077, Free PMC Article
    2. Anti-silencing factor Epe1 associates with SAGA to regulate transcription within heterochromatin. Bao K, et al. Genes Dev, 2019 Jan 1. PMID 30573453, Free PMC Article
    3. The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8. Helmlinger D, et al. Genes Dev, 2008 Nov 15. PMID 19056896, Free PMC Article
    4. Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex. Helmlinger D, et al. EMBO J, 2011 Jun 3. PMID 21642955, Free PMC Article
    5. TORC1 and TORC2 converge to regulate the SAGA co-activator in response to nutrient availability. Laboucarié T, et al. EMBO Rep, 2017 Dec. PMID 29079657, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of SAGA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SAGA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SAGA complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    SAGA complex subunit Hfi1/Ada1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3578033..3579719 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022412.3 → NP_596492.1  SAGA complex subunit Hfi1/Ada1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596492.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94301
      Conserved Domains (1) summary
      pfam12767
      Location:17 → 250
      SAGA-Tad1; Transcriptional regulator of RNA polII, SAGA, subunit
    Nucleotide Protein
    Heading Accession and Version

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