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    tts1 tetra-spanning protein 1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539923, updated on 18-Sep-2024

    Summary

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    Official Symbol
    tts1
    Official Full Name
    tetra-spanning protein 1
    Primary source
    PomBase:SPBC1539.04
    Locus tag
    SPOM_SPBC1539.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See tts1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (4368342..4369816)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene argininosuccinate lyase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene COG complex subunit Cog3 Neighboring gene acyl-coenzyme A binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tts1, the fission yeast homologue of the TMEM33 family, functions in NE remodeling during mitosis. Zhang D, et al. Mol Biol Cell, 2014 Oct 1. PMID 25103238, Free PMC Article
    2. The cortical ER network limits the permissive zone for actomyosin ring assembly. Zhang D, et al. Curr Biol, 2010 Jun 8. PMID 20434336
    3. Characterization of cwl1+, a gene from Schizosaccharomyces pombe whose overexpression causes cell lysis. Godoy C, et al. Yeast, 1996 Aug. PMID 8873452
    4. Plasma membrane tethering of the cortical ER necessitates its finely reticulated architecture. Zhang D, et al. Curr Biol, 2012 Nov 6. PMID 23041194
    5. Characterization of nuclear pore complex components in fission yeast Schizosaccharomyces pombe. Asakawa H, et al. Nucleus, 2014 Mar-Apr. PMID 24637836, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. in addition to maintaining the cortical endoplasmic reticulum network, Tts1 also plays a role in nuclear envelope remodeling during mitosis
      Title: Tts1, the fission yeast homologue of the TMEM33 family, functions in NE remodeling during mitosis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum tubular network membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in endoplasmic reticulum tubular network organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic spindle pole body insertion into the nuclear envelope IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in mitotic spindle pole body localization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in nuclear membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus HDA PubMed 
    is_active_in cell division site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cortical endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum tubular network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nuclear membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of nuclear pore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tetra-spanning protein 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      4368342..4369816
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023838.3 → NP_596818.1  tetra-spanning protein 1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596818.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9Y7Z5
      Conserved Domains (1) summary
      pfam03661
      Location:23 → 256
      UPF0121; uncharacterized protein family (UPF0121)
    Nucleotide Protein
    Heading Accession and Version

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