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    mcs2 transcription factor TFIIH complex cyclin Mcs2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540555, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mcs2
    Official Full Name
    transcription factor TFIIH complex cyclin Mcs2
    Primary source
    PomBase:SPBP16F5.02
    Locus tag
    SPOM_SPBP16F5.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See mcs2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (1892980..1894408)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GDP/GTP exchange factor Spo14 Neighboring gene ncRNA Neighboring gene SAGA complex, phosphatidylinositol pseudokinase subunit Tra1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the fission yeast mcs2 cyclin and its associated protein kinase activity. Molz L, et al. EMBO J, 1993 Apr. PMID 8467814, Free PMC Article
    2. Schizosaccharomyces pombe Mop1-Mcs2 is related to mammalian CAK. Damagnez V, et al. EMBO J, 1995 Dec 15. PMID 8557036, Free PMC Article
    3. Cdc2 activation in fission yeast depends on Mcs6 and Csk1, two partially redundant Cdk-activating kinases (CAKs). Lee KM, et al. Curr Biol, 1999 Apr 22. PMID 10226032
    4. Fission yeast Csk1 is a CAK-activating kinase (CAKAK). Hermand D, et al. EMBO J, 1998 Dec 15. PMID 9857180, Free PMC Article
    5. Identification of a cdk-activating kinase in fission yeast. Buck V, et al. EMBO J, 1995 Dec 15. PMID 8557037, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA polymerase II general transcription initiation factor activity IC
    Inferred by Curator
    more info
    		  
    enables cyclin-dependent protein serine/threonine kinase activator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activator activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of transcription factor TFIIK complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIIK complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor TFIIH complex cyclin Mcs2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1892980..1894408
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021676.3 → NP_595776.1  transcription factor TFIIH complex cyclin Mcs2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595776.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P36613
      Conserved Domains (4) summary
      TIGR00569
      Location:6 → 307
      ccl1; cyclin ccl1
      TIGR04235
      Location:20 → 109
      seadorna_VP4; seadornavirus VP4 protein
      cd00043
      Location:77 → 156
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
      cl00050
      Location:168 → 239
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
    Nucleotide Protein
    Heading Accession and Version

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