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    FucTD alpha1,3-fucosyltransferase D [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38164, updated on 27-Dec-2024

    Summary

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    Official Symbol
    FucTDprovided by FlyBase
    Official Full Name
    alpha1,3-fucosyltransferase Dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035217
    Locus tag
    Dmel_CG9169
    See related
    AllianceGenome:FB:FBgn0035217
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9169; Dmel\CG9169
    Summary
    Predicted to enable fucosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See FucTD in Genome Data Viewer
    Location:
    62A1-62A1; 3-0.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1416231..1417933)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1416231..1417933)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Protein tyrosine phosphatase 61F Neighboring gene transfer RNA:Glutamic acid-CTC 3-9 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Stromalin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Modulation of neural carbohydrate epitope expression in Drosophila melanogaster cells. Rendic D, et al. J Biol Chem, 2006 Feb 10. PMID 16314421
    2. Neural-specific α3-fucosylation of N-linked glycans in the Drosophila embryo requires fucosyltransferase A and influences developmental signaling associated with O-glycosylation. Rendić D, et al. Glycobiology, 2010 Nov. PMID 20688784, Free PMC Article
    3. Affecting Rhomboid-3 function causes a dilated heart in adult Drosophila. Yu L, et al. PLoS Genet, 2010 May 27. PMID 20523889, Free PMC Article
    4. Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism. Roos C, et al. J Biol Chem, 2002 Feb 1. PMID 11698403
    5. A genetic screen in Drosophila reveals the role of fucosylation in host susceptibility to Candida infection. Glittenberg MT, et al. Dis Model Mech, 2022 May 1. PMID 35142345, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables fucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    alpha1,3-fucosyltransferase D
    Names
    CG9169-PA
    FucTD-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1416231..1417933
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138263.2 → NP_612107.1  alpha1,3-fucosyltransferase D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_612107.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T8Y7, Q9W0F6
      Related
      FBpp0072577
      Conserved Domains (2) summary
      pfam00852
      Location:268 → 427
      Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
      pfam17039
      Location:125 → 228
      Glyco_tran_10_N; Fucosyltransferase, N-terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T8Y7 Q8T8Y7
    Q9W0F6 Q9W0F6

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