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    Acsbg3 acyl-CoA synthetase bubblegum family member 3 [ Mus musculus (house mouse) ]

    Gene ID: 78625, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Acsbg3provided by MGI
    Official Full Name
    acyl-CoA synthetase bubblegum family member 3provided by MGI
    Primary source
    MGI:MGI:1925875
    See related
    Ensembl:ENSMUSG00000024209 AllianceGenome:MGI:1925875
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700026H02; 1700061G19Rik
    Summary
    Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid biosynthetic process. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 46.4) and bladder adult (RPKM 1.5) See more
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    Genomic context

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    See Acsbg3 in Genome Data Viewer
    Location:
    17 D; 17 29.55 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (57182453..57195907)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (56875452..56889855)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene regulatory factor X, 2 (influences HLA class II expression) Neighboring gene predicted gene, 41604 Neighboring gene STARR-positive B cell enhancer ABC_E5625 Neighboring gene STARR-seq mESC enhancer starr_42905 Neighboring gene acyl-CoA synthetase bubblegum family member 2 Neighboring gene STARR-seq mESC enhancer starr_42911 Neighboring gene myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 Neighboring gene STARR-positive B cell enhancer ABC_E1946 Neighboring gene alkaline ceramidase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables long-chain fatty acid-CoA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in long-chain fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC78625

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030141.2 → NP_084417.1  uncharacterized protein LOC78625

      See identical proteins and their annotated locations for NP_084417.1

      Status: VALIDATED

      Source sequence(s)
      AC073683, BC116283
      Consensus CDS
      CCDS37666.1
      UniProtKB/TrEMBL
      Q08EE8
      Related
      ENSMUSP00000025048.7, ENSMUST00000025048.7
      Conserved Domains (2) summary
      cd05933
      Location:95 → 700
      ACSBG_like; Bubblegum-like very long-chain fatty acid CoA synthetase (VL-FACS)
      COG1022
      Location:74 → 701
      FAA1; Long-chain acyl-CoA synthetase (AMP-forming) [Lipid transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      57182453..57195907
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006525141.3 → XP_006525204.1  uncharacterized protein LOC78625 isoform X1

      Conserved Domains (1) summary
      cl17068
      Location:95 → 334
      AFD_class_I; Adenylate forming domain, Class I superfamily

    RNA

    1. XR_385395.4 RNA Sequence

    2. XR_385396.5 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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