npr-43 G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: npr-43
Official Full Name: G-protein coupled receptors family 1 profile domain-containing protein
Primary source: WormBase:WBGene00010143
Locus tag: CELE_F56A12.2
See related: AllianceGenome:WB:WBGene00010143
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See npr-43 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 8

Sequence:: Chromosome: V; NC_003283.11 (14375996..14379086, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F56A12.2 (e-PCR)
- UniSTS:307710

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables neuropeptide receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in neuropeptide signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: G-protein coupled receptors family 1 profile domain-containing protein

NP_001360540.1

Confirmed by transcript evidence

NP_506564.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

14375996..14379086 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_074163.5 → NP_506564.2 G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_506564.2

Status: REVIEWED

UniProtKB/TrEMBL

O45571

Conserved Domains (2) summary

cd14964
Location:32 → 58

7tm_GPCRs; TM helix 1 [structural motif]

cl28897
Location:31 → 373

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
NM_001373157.2 → NP_001360540.1 G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A486WYF3

Conserved Domains (2) summary

cd14964
Location:32 → 58

7tm_GPCRs; TM helix 1 [structural motif]

cl28897
Location:31 → 373

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily