ppap2d phosphatidic acid phosphatase type 2D [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ppap2dprovided by ZNC
Official Full Name: phosphatidic acid phosphatase type 2Dprovided by ZNC
Primary source: ZFIN:ZDB-GENE-061201-42
See related: Ensembl:ENSDARG00000069940 AllianceGenome:ZFIN:ZDB-GENE-061201-42
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ppap2b; zgc:158309
Summary: Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; phospholipid metabolic process; and signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (47322494..47387396)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (50511854..50576756)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables phosphatidate phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidate phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in phospholipid dephosphorylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in phospholipid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phospholipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in signal transduction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: phosphatidic acid phosphatase type 2D

Names: phosphatidic acid phosphatase type 2B

NP_001073447.1

EC 3.1.3.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001079978.1 → NP_001073447.1 phosphatidic acid phosphatase type 2D

See identical proteins and their annotated locations for NP_001073447.1

Status: PROVISIONAL

Source sequence(s)

BC127580

UniProtKB/TrEMBL

A0A0R4ISR5, A0A8M1NCJ2, A0PJR3

Related

ENSDARP00000092978.4, ENSDART00000102202.6

Conserved Domains (1) summary

cd03384
Location:145 → 291

PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...