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    si:ch211-241e1.3 si:ch211-241e1.3 [ Danio rerio (zebrafish) ]

    Gene ID: 567640, updated on 9-Dec-2024

    Summary

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    Official Symbol
    si:ch211-241e1.3provided by ZNC
    Official Full Name
    si:ch211-241e1.3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-230
    See related
    Ensembl:ENSDARG00000022615 AllianceGenome:ZFIN:ZDB-GENE-030131-230
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb17h02; wu:fb17h02
    Summary
    Predicted to be an extracellular matrix structural constituent. Predicted to be involved in animal organ morphogenesis; axon guidance; and tissue development. Predicted to act upstream of or within several processes, including cell adhesion; regulation of cell migration; and regulation of embryonic development. Predicted to be located in extracellular region and membrane. Predicted to be active in basement membrane. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and lung small cell carcinoma. Orthologous to human LAMA3 (laminin subunit alpha 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See si:ch211-241e1.3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (944341..985417, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (1073933..1115057, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene si:ch211-241e1.5 Neighboring gene receptor (TNFRSF)-interacting serine-threonine kinase 1, like Neighboring gene zinc finger protein 239 Neighboring gene calcium channel, voltage-dependent, R type, alpha 1E subunit b Neighboring gene RNA polymerase II subunit D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages. Nagendran M, et al. Development, 2015 Jan 15. PMID 25519245, Free PMC Article
    2. Screen for genes differentially expressed during regeneration of the zebrafish caudal fin. Padhi BK, et al. Dev Dyn, 2004 Nov. PMID 15376328
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of embryonic development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    laminin subunit alpha-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      944341..985417 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_690939.9 → XP_696031.7  laminin subunit alpha-3

      UniProtKB/TrEMBL
      A0A8N7TFA0
      Related
      ENSDARP00000119869.1, ENSDART00000140540.3
    Nucleotide Protein Strain
    Heading Accession and Version

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