ints1 integrator complex subunit 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ints1provided by ZNC
Official Full Name: integrator complex subunit 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6523
See related: Ensembl:ENSDARG00000100419 AllianceGenome:ZFIN:ZDB-GENE-030131-6523
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fa14a05; wu:fa14a05; wu:fa55a06
Summary: Predicted to be involved in U2 snRNA 3'-end processing. Predicted to be part of integrator complex. Is expressed in brain and eye. Used to study cataract and neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies. Orthologous to human INTS1 (integrator complex subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (42999276..43060971)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (42293211..42354956)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

A deleterious variant of INTS1 leads to disrupted sleep-wake cycles.
Title: A deleterious variant of INTS1 leads to disrupted sleep-wake cycles.

Submit: New GeneRIF Correction

Process	Evidence Code	Pubs
involved_in U2 snRNA 3'-end processing	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within U2 snRNA 3'-end processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of integrator complex	IBA Inferred from Biological aspect of Ancestor more info
part_of integrator complex	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain