U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    dtwd1 DTW domain containing 1 [ Danio rerio (zebrafish) ]

    Gene ID: 449778, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    dtwd1provided by ZNC
    Official Full Name
    DTW domain containing 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041010-23
    See related
    Ensembl:ENSDARG00000111509 AllianceGenome:ZFIN:ZDB-GENE-041010-23
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb34c05; zgc:103637
    Summary
    Predicted to enable tRNA-uridine aminocarboxypropyltransferase activity. Predicted to be involved in tRNA modification. Predicted to act upstream of or within tRNA processing. Predicted to be active in nucleus. Orthologous to human DTWD1 (DTW domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See dtwd1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (5454254..5457108)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (5390234..5393088, complement)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene SECIS binding protein 2-like Neighboring gene uncharacterized LOC103909114 Neighboring gene fibroblast growth factor 7 Neighboring gene NAD(P) transhydrogenase, mitochondrial Neighboring gene uncharacterized LOC103909115 Neighboring gene muscle-specific beta 1 integrin binding protein 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Pervasive yet nonuniform contributions of Dcp2 and Cnot7 to maternal mRNA clearance in zebrafish. Mishima Y, et al. Genes Cells, 2017 Jul. PMID 28557307
    2. Serial analysis of gene expression in the skeletal muscles of zebrafish fed with a methylmercury-contaminated diet. Cambier S, et al. Environ Sci Technol, 2010 Jan 1. PMID 20039754
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables tRNA-uridine aminocarboxypropyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables tRNA-uridine aminocarboxypropyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA-uridine aminocarboxypropyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA modification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA modification ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    tRNA-uridine aminocarboxypropyltransferase 1
    Names
    DTW domain-containing protein 1
    NP_001005951.2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005951.2 → NP_001005951.2  tRNA-uridine aminocarboxypropyltransferase 1

      Status: PROVISIONAL

      Source sequence(s)
      EH463350, EH540548, EH553437
      UniProtKB/Swiss-Prot
      Q5XJ56
      UniProtKB/TrEMBL
      A0A2R8Q4B6, A0A8M1N2M0
      Related
      ENSDARP00000145731.1, ENSDART00000192649.1
      Conserved Domains (1) summary
      pfam03942
      Location:42 → 241
      DTW; DTW domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      5454254..5457108
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XJ56.1 GenPept UniProtKB/Swiss-Prot:Q5XJ56

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools