ppp2cb protein phosphatase 2, catalytic subunit, beta isozyme [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ppp2cbprovided by ZNC
Official Full Name: protein phosphatase 2, catalytic subunit, beta isozymeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2487
See related: Ensembl:ENSDARG00000099241 AllianceGenome:ZFIN:ZDB-GENE-040426-2487
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb17h07; fc05c02; fk24a01; zgc:55808; zgc:77172; wu:fb17h07; wu:fc05c02; wu:fk24a01
Summary: Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in mitotic cell cycle. Predicted to be located in chromosome, centromeric region; cytoplasm; and spindle pole. Predicted to be active in cytosol. Orthologous to human PPP2CB (protein phosphatase 2 catalytic subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (7593238..7617473)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (7634538..7658773)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc05c02.x1 (e-PCR)
- UniSTS:203701

fk24a01.y1 (e-PCR)
- UniSTS:200676

fb17h07.x1 (e-PCR)
- UniSTS:202996

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables myosin phosphatase activity	IEA Inferred from Electronic Annotation more info
enables phosphoprotein phosphatase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in chromosome, centromeric region	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in spindle pole	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

NP_998458.1

EC 3.1.3.16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213293.1 → NP_998458.1 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

See identical proteins and their annotated locations for NP_998458.1

Status: PROVISIONAL

Source sequence(s)

BC065680

UniProtKB/TrEMBL

Q6P0B7, Q7ZVE7, Q803G3

Related

ENSDARP00000140225.1, ENSDART00000162617.2

Conserved Domains (1) summary

cd07415
Location:9 → 293

MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain