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    slc35a4 solute carrier family 35 member A4 [ Danio rerio (zebrafish) ]

    Gene ID: 777628, updated on 4-Jan-2025

    Summary

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    Official Symbol
    slc35a4provided by ZNC
    Official Full Name
    solute carrier family 35 member A4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061103-595
    See related
    Ensembl:ENSDARG00000062379 AllianceGenome:ZFIN:ZDB-GENE-061103-595
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc56f11; wu:fc56f11; zgc:153507
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to act upstream of or within pyrimidine nucleotide-sugar transmembrane transport. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi membrane. Orthologous to human SLC35A4 (solute carrier family 35 member A4). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See slc35a4 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (3062608..3071623, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (2811491..2820545, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene si:dkey-201i24.3 Neighboring gene CD74 molecule, major histocompatibility complex, class II invariant chain a Neighboring gene HMG box domain containing 3 Neighboring gene si:zfos-1069f5.1 Neighboring gene colony stimulating factor 1 receptor, a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables pyrimidine nucleotide-sugar transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within pyrimidine nucleotide-sugar transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    probable UDP-sugar transporter protein SLC35A4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001256043.2 → NP_001242972.1  probable UDP-sugar transporter protein SLC35A4 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.
      Source sequence(s)
      CU468924, FP102516
      UniProtKB/Swiss-Prot
      A0JMG9
      UniProtKB/TrEMBL
      A0A8M1P4A4, F1R3E4
      Conserved Domains (1) summary
      cl23754
      Location:93 → 312
      EamA; EamA-like transporter family

    RNA

    1. NR_045688.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      CU468924, FP102516

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      3062608..3071623 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017359031.3 → XP_017214520.1  probable UDP-sugar transporter protein SLC35A4 isoform X1

      UniProtKB/Swiss-Prot
      A0JMG9
      UniProtKB/TrEMBL
      A0A8M1P4A4, F1R3E4
      Related
      ENSDARP00000084629.3, ENSDART00000090196.5
      Conserved Domains (1) summary
      cl23754
      Location:93 → 312
      EamA; EamA-like transporter family

    2. XM_068213252.1 → XP_068069353.1  probable UDP-sugar transporter protein SLC35A4 isoform X2

      Related
      ENSDARP00000152497.1, ENSDART00000193729.1

    RNA

    1. XR_011006103.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0JMG9.1 GenPept UniProtKB/Swiss-Prot:A0JMG9

    Gene LinkOut

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