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    myl9b myosin, light chain 9b, regulatory [ Danio rerio (zebrafish) ]

    Gene ID: 406493, updated on 9-Dec-2024

    Summary

    Official Symbol
    myl9bprovided by ZNC
    Official Full Name
    myosin, light chain 9b, regulatoryprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2296
    See related
    Ensembl:ENSDARG00000008030 AllianceGenome:ZFIN:ZDB-GENE-040426-2296
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    myl9; zgc:77916
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in myofibril assembly. Predicted to be active in myofibril and stress fiber. Is expressed in smooth muscle cell. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy and megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human MYL9 (myosin light chain 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See myl9b in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (1787280..1799330)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (1652141..1664191)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene zgc:113442 Neighboring gene N-terminal asparagine amidase Neighboring gene homeobox protein TGIF2 Neighboring gene discs, large (Drosophila) homolog-associated protein 4b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables myosin heavy chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in myofibril assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in myofibril IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of myosin II complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in stress fiber IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    myosin regulatory light polypeptide 9b
    Names
    myl9l
    myosin, light polypeptide 9, regulatory

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213212.1NP_998377.1  myosin regulatory light polypeptide 9b

      See identical proteins and their annotated locations for NP_998377.1

      Status: PROVISIONAL

      Source sequence(s)
      BC068220
      UniProtKB/TrEMBL
      A0A8M1PES6, A0A8M9PKQ2, F1QYK9, Q6NVA6
      Related
      ENSDARP00000104211.2, ENSDART00000113505.5
      Conserved Domains (1) summary
      COG5126
      Location:19169
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      1787280..1799330
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)