frem3 Fras1 related extracellular matrix 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: frem3provided by ZNC
Official Full Name: Fras1 related extracellular matrix 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9788
See related: Ensembl:ENSDARG00000074677 AllianceGenome:ZFIN:ZDB-GENE-030131-9788
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb348; fc44f01; sb:cb348; wu:fc44f01
Summary: Predicted to be involved in anatomical structure morphogenesis. Predicted to act upstream of or within cell adhesion and cell communication. Predicted to be located in membrane. Predicted to be active in collagen-containing extracellular matrix. Is expressed in several structures, including endoderm; forebrain; head; median fin fold; and musculature system. Orthologous to human FREM3 (FRAS1 related extracellular matrix 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (35614667..35653718, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (34882640..34921691, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The fish gene complement includes fras1, frem1a, frem1b, frem2a, frem2b, and frem3, which display complex overlapping and complementary expression patterns in developing tissues including the pharyngeal arches, hypochord, musculature, and otic vesicle.
Title: Expression of the fras1/frem gene family during zebrafish development and fin morphogenesis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

fc44f01.x1 (e-PCR)
- UniSTS:188176

fa01f01.s1 (e-PCR)
- UniSTS:189488

fc70c05.y1 (e-PCR)
- UniSTS:194300

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell communication	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in collagen-containing extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: FRAS1-related extracellular matrix protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.