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    rabl2 RAB, member of RAS oncogene family-like 2 [ Danio rerio (zebrafish) ]

    Gene ID: 561568, updated on 27-Dec-2024

    Summary

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    Official Symbol
    rabl2provided by ZNC
    Official Full Name
    RAB, member of RAS oncogene family-like 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060503-464
    See related
    Ensembl:ENSDARG00000063321 AllianceGenome:ZFIN:ZDB-GENE-060503-464
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkeyp-1h4.2
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Orthologous to human RABL2A (RAB, member of RAS oncogene family like 2A) and RABL2B (RAB, member of RAS oncogene family like 2B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rabl2 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (7639401..7649861)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (7680444..7690926)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 35-30 Neighboring gene ciliary microtubule associated protein 1B Neighboring gene SH3 and multiple ankyrin repeat domains 3a Neighboring gene golgin subfamily A member 6-like protein 22 Neighboring gene arylsulfatase A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Isolation, sequence identification and expression profile of three novel genes Rab2A, Rab3A and Rab7A from Black-boned sheep (Ovis aries). He YD, et al. Mol Biol (Mosk), 2010 Jan-Feb. PMID 20198855
    2. Deficiency of the minor spliceosome component U4atac snRNA secondarily results in ciliary defects in human and zebrafish. Khatri D, et al. Proc Natl Acad Sci U S A, 2023 Feb 28. PMID 36802443, Free PMC Article
    3. Intestinal dysmotility in a zebrafish (Danio rerio) shank3a;shank3b mutant model of autism. James DM, et al. Mol Autism, 2019. PMID 30733854, Free PMC Article
    4. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RAB, member of RAS oncogene family-like 2
    Names
    RAB, member of RAS oncogene family-like 2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044963.2 → NP_001038428.1  RAB, member of RAS oncogene family-like 2

      See identical proteins and their annotated locations for NP_001038428.1

      Status: PROVISIONAL

      Source sequence(s)
      BC134982
      UniProtKB/TrEMBL
      A0A2R8RZV9, F6NK56, Q1L8G2
      Related
      ENSDARP00000086848.5, ENSDART00000092416.6
      Conserved Domains (2) summary
      cd04124
      Location:20 → 180
      RabL2; Rab GTPase-like family 2 (Rab-like2)
      smart00175
      Location:20 → 169
      RAB; Rab subfamily of small GTPases

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      7639401..7649861
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009293419.4 → XP_009291694.1  RAB, member of RAS oncogene family-like 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M3AJE6
      Conserved Domains (2) summary
      smart00175
      Location:20 → 182
      RAB; Rab subfamily of small GTPases
      cl21455
      Location:20 → 193
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395003.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      275282..286309
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395333.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      87591..98051
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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