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    tcimb transcriptional and immune response regulator b [ Danio rerio (zebrafish) ]

    Gene ID: 558746, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tcimbprovided by ZNC
    Official Full Name
    transcriptional and immune response regulator bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8182
    See related
    Ensembl:ENSDARG00000076858 AllianceGenome:ZFIN:ZDB-GENE-030131-8182
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj58g06; wu:fj58g06
    Summary
    Is expressed in brain; hematopoietic stem cell; and trunk vasculature. Orthologous to human TCIM (transcriptional and immune response regulator). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See tcimb in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (20256391..20257177)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (20299027..20299795)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine (serotonin) receptor 7b Neighboring gene protein phosphatase 3, catalytic subunit, gamma isozyme, b Neighboring gene zinc finger, matrin-type 4b Neighboring gene uncharacterized LOC137496581

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TC1(C8orf4) is a novel endothelial inflammatory regulator enhancing NF-kappaB activity. Kim J, et al. J Immunol, 2009 Sep 15. PMID 19684084
    2. Arap3 is dysregulated in a mouse model of hypotrichosis-lymphedema-telangiectasia and regulates lymphatic vascular development. Kartopawiro J, et al. Hum Mol Genet, 2014 Mar 1. PMID 24163130
    3. Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish. Gomez G, et al. PLoS One, 2012. PMID 22438865, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    transcriptional and immune response regulator b
    Names
    tc1b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001386670.1 → NP_001373599.1  transcriptional and immune response regulator b

      Status: VALIDATED

      Source sequence(s)
      CR381599
      Related
      ENSDARP00000101428.2, ENSDART00000111097.3
      Conserved Domains (1) summary
      pfam15063
      Location:4 → 78
      TC1; Thyroid cancer protein 1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      20256391..20257177
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395287.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      171038..171829
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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