cant1a calcium activated nucleotidase 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cant1aprovided by ZNC
Official Full Name: calcium activated nucleotidase 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2441
See related: Ensembl:ENSDARG00000012192 AllianceGenome:ZFIN:ZDB-GENE-040426-2441
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cant1; entpd8; zgc:85724
Summary: Predicted to enable GDP phosphatase activity and UDP phosphatase activity. Predicted to be involved in proteoglycan biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Desbuquois dysplasia and multiple epiphyseal dysplasia 7. Orthologous to human CANT1 (calcium activated nucleotidase 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (57747716..57765169, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (57677192..57694645, complement)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fj88e03.y1 (e-PCR)
- UniSTS:200214

fj88e09.x1 (e-PCR)
- UniSTS:200216

fj66d05.x1 (e-PCR)
- UniSTS:199790

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GDP phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleoside diphosphate phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proteoglycan biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: soluble calcium-activated nucleotidase 1

Names: calcium activated nucleotidase 1

NP_999908.1

EC 3.6.1.6

XP_005171699.1

EC 3.6.1.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.