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    marchf9 membrane-associated ring finger (C3HC4) 9 [ Danio rerio (zebrafish) ]

    Gene ID: 100003493, updated on 9-Dec-2024

    Summary

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    Official Symbol
    marchf9provided by ZNC
    Official Full Name
    membrane-associated ring finger (C3HC4) 9provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081031-71
    See related
    Ensembl:ENSDARG00000055740 AllianceGenome:ZFIN:ZDB-GENE-081031-71
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    march9; si:dkey-229p15.1
    Summary
    Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in membrane. Orthologous to human MARCHF9 (membrane associated ring-CH-type finger 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See marchf9 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (36771594..36799260)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (36648166..36676799)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Neighboring gene tetraspanin 31 Neighboring gene microRNA mir-2191 Neighboring gene homeodomain interacting protein kinase 1a Neighboring gene ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Zebrafish MARCH7 negatively regulates IFN antiviral response by degrading TBK1. Xiong ST, et al. Int J Biol Macromol, 2023 Jun 15. PMID 37054851
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase MARCH9; E3 ubiquitin-protein ligase MARCHF9
    XP_001339845.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      36771594..36799260
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001339809.9 → XP_001339845.1  E3 ubiquitin-protein ligase MARCHF9

      UniProtKB/TrEMBL
      A0A8M1PSE0, E7F4X3
      Related
      ENSDARP00000072702.5, ENSDART00000078240.6
      Conserved Domains (1) summary
      smart00744
      Location:105 → 151
      RINGv; The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins
    Nucleotide Protein
    Heading Accession and Version

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