coa8 cytochrome c oxidase assembly factor 8 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: coa8provided by ZNC
Official Full Name: cytochrome c oxidase assembly factor 8provided by ZNC
Primary source: ZFIN:ZDB-GENE-090313-66
See related: Ensembl:ENSDARG00000092473 AllianceGenome:ZFIN:ZDB-GENE-090313-66
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: apopt1; si:ch211-194h13.2
Summary: Predicted to act upstream of or within intrinsic apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 17. Orthologous to human COA8 (cytochrome c oxidase assembly factor 8). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (15800742..15814776)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (15669750..15683784)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within intrinsic apoptotic signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytochrome c oxidase assembly factor 8

Names: apoptogenic 1, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001145619.1 → NP_001139091.1 cytochrome c oxidase assembly factor 8

Status: PROVISIONAL

Source sequence(s)

BX569782

UniProtKB/TrEMBL

A0A8M1NTA1, B8A5M9

Related

ENSDARP00000122568.1, ENSDART00000146234.2

Conserved Domains (1) summary

pfam10231
Location:59 → 185

DUF2315; uncharacterized conserved protein (DUF2315)