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    agfg1b ArfGAP with FG repeats 1b [ Danio rerio (zebrafish) ]

    Gene ID: 393560, updated on 9-Dec-2024

    Summary

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    Official Symbol
    agfg1bprovided by ZNC
    Official Full Name
    ArfGAP with FG repeats 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1520
    See related
    Ensembl:ENSDARG00000019526 AllianceGenome:ZFIN:ZDB-GENE-040426-1520
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:66055
    Summary
    Predicted to enable GTPase activator activity and metal ion binding activity. Predicted to be involved in acrosome assembly; intermediate filament organization; and spermatid nucleus differentiation. Predicted to be active in cytoplasmic vesicle. Orthologous to human AGFG1 (ArfGAP with FG repeats 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See agfg1b in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (16460331..16479291)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (16791722..16810701)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene ATR serine/threonine kinase Neighboring gene zgc:110269 Neighboring gene odorant receptor 131-2-like Neighboring gene F-box protein 36b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Depletion of Tissue-Specific Ion Transporters Causes Differential Expression of PRL Targets in Response to Increased Levels of Endogenous PRL. Shu T, et al. Front Endocrinol (Lausanne), 2018. PMID 30515132, Free PMC Article
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC66055

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in acrosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intermediate filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spermatid nucleus differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    arf-GAP domain and FG repeat-containing protein 1b
    Names
    DKEYP-13A3.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200588.2 → NP_956882.2  arf-GAP domain and FG repeat-containing protein 1b

      Status: PROVISIONAL

      Source sequence(s)
      CR377211
      UniProtKB/TrEMBL
      A0A8M1PFE8, B0UXL9
      Related
      ENSDARP00000119105.1, ENSDART00000145107.3
      Conserved Domains (1) summary
      smart00105
      Location:17 → 135
      ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      16460331..16479291
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068223332.1 → XP_068079433.1  arf-GAP domain and FG repeat-containing protein 1b isoform X2

    2. XM_005163316.5 → XP_005163373.1  arf-GAP domain and FG repeat-containing protein 1b isoform X1

      UniProtKB/TrEMBL
      A0A8M2BAC3
      Conserved Domains (1) summary
      smart00105
      Location:17 → 135
      ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    Nucleotide Protein
    Heading Accession and Version

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