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    sccpdhb saccharopine dehydrogenase b [ Danio rerio (zebrafish) ]

    Gene ID: 407665, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sccpdhbprovided by ZNC
    Official Full Name
    saccharopine dehydrogenase bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041010-211
    See related
    Ensembl:ENSDARG00000024564 AllianceGenome:ZFIN:ZDB-GENE-041010-211
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb4; sb:cb4; zgc:101527
    Summary
    Predicted to be involved in glycolipid biosynthetic process. Predicted to be located in membrane. Predicted to be active in lipid droplet. Is expressed in neural tube; primary neurons; and spinal cord. Orthologous to human SCCPDH (saccharopine dehydrogenase (putative)). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See sccpdhb in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (34967423..34985555, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (35064544..35082676, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and EF-hand domain containing 1a Neighboring gene synaptosome associated protein 25a Neighboring gene uncharacterized LOC110438184 Neighboring gene consortin, connexin sorting protein b Neighboring gene uncharacterized LOC137488670 Neighboring gene kinesin family member 26Bb

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC101527

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in glycolipid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in lipid droplet IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    saccharopine dehydrogenase b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005574.1 → NP_001005574.1  saccharopine dehydrogenase b

      See identical proteins and their annotated locations for NP_001005574.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083193
      UniProtKB/TrEMBL
      Q5XJV1
      Related
      ENSDARP00000035945.4, ENSDART00000037065.6
      Conserved Domains (2) summary
      COG3268
      Location:6 → 427
      COG3268; Uncharacterized conserved protein, related to short-chain dehydrogenases [Function unknown]
      pfam03435
      Location:14 → 151
      Sacchrp_dh_NADP; Saccharopine dehydrogenase NADP binding domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      34967423..34985555 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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