sstr5 somatostatin receptor 5 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sstr5provided by ZNC
Official Full Name: somatostatin receptor 5provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2502
See related: Ensembl:ENSDARG00000101655 AllianceGenome:ZFIN:ZDB-GENE-040426-2502
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:85682
Summary: Predicted to enable neuropeptide binding activity and somatostatin receptor activity. Predicted to be involved in cellular response to glucocorticoid stimulus; neuropeptide signaling pathway; and regulation of insulin secretion. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in neuron projection and plasma membrane. Human ortholog(s) of this gene implicated in bipolar disorder. Orthologous to human SSTR5 (somatostatin receptor 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (11101552..11122914)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (11135010..11156371)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables neuropeptide binding	IBA Inferred from Biological aspect of Ancestor more info
enables somatostatin receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables somatostatin receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in cellular response to glucocorticoid stimulus	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuropeptide signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of insulin secretion	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in neuron projection	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: somatostatin receptor type 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213297.1 → NP_998462.1 somatostatin receptor type 5

See identical proteins and their annotated locations for NP_998462.1

Status: PROVISIONAL

Source sequence(s)

BC068356

UniProtKB/TrEMBL

Q6NV10

Related

ENSDARP00000132886.1, ENSDART00000172103.2

Conserved Domains (2) summary

pfam00001
Location:51 → 300

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:42 → 241

7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007114.7 Reference GRCz11 Primary Assembly

Range

11101552..11122914

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005164434.5 → XP_005164491.1 somatostatin receptor type 5 isoform X2

UniProtKB/TrEMBL

A0A8M2BBL8

Conserved Domains (2) summary

pfam00001
Location:51 → 300

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:42 → 241

7tm_4; Olfactory receptor
XM_005164433.4 → XP_005164490.1 somatostatin receptor type 5 isoform X1

UniProtKB/TrEMBL

A0A8M2BBV6

Conserved Domains (2) summary

pfam00001
Location:51 → 300

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:42 → 241

7tm_4; Olfactory receptor