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    mfsd4aa major facilitator superfamily domain containing 4Aa [ Danio rerio (zebrafish) ]

    Gene ID: 393503, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mfsd4aaprovided by ZNC
    Official Full Name
    major facilitator superfamily domain containing 4Aaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1643
    See related
    Ensembl:ENSDARG00000023768 AllianceGenome:ZFIN:ZDB-GENE-040426-1643
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mfsd4; mfsd4a; zgc:66461
    Summary
    Predicted to enable D-glucose transmembrane transporter activity. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Is expressed in diencephalon and yolk syncytial layer. Orthologous to human MFSD4A (major facilitator superfamily domain containing 4A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See mfsd4aa in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (38429319..38458395)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (38162114..38190945)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene BLACAT1 overlapping LEMD1 locus Neighboring gene microRNA 135c-1 Neighboring gene cyclin dependent kinase 18 Neighboring gene si:ch211-117k10.3 Neighboring gene ETS transcription factor ELK4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression. Perland E, et al. Open Biol, 2017 Sep. PMID 28878041, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC66461

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables D-glucose transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    major facilitator superfamily domain-containing protein 4A
    Names
    major facilitator superfamily domain containing 4
    major facilitator superfamily domain containing 4a
    major facilitator superfamily domain-containing protein 4
    major facilitator superfamily domain-containing protein 4-A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200531.2 → NP_956825.2  major facilitator superfamily domain-containing protein 4A

      Status: VALIDATED

      Source sequence(s)
      AL929286, FQ311877
      UniProtKB/Swiss-Prot
      Q7SXB7
      Related
      ENSDARP00000032062.8, ENSDART00000029157.9

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      38429319..38458395
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7SXB7.1 GenPept UniProtKB/Swiss-Prot:Q7SXB7

    Gene LinkOut

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