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    T06D8.2 UVR domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174711, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T06D8.2
    Official Full Name
    UVR domain-containing protein
    Primary source
    WormBase:WBGene00011523
    Locus tag
    CELE_T06D8.2
    See related
    AllianceGenome:WB:WBGene00011523
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in cilium. Human ortholog(s) of this gene implicated in Joubert syndrome 25 and autosomal recessive intellectual developmental disorder 77. Orthologous to human CEP104 (centrosomal protein 104). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T06D8.2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    13
    Sequence:
    Chromosome: II; NC_003280.10 (11226679..11232835)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene EOG090X04TT Neighboring gene putative holocytochrome-c-type synthase Neighboring gene FUN14 domain-containing protein fndc-1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    UVR domain-containing protein
    NP_496400.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11226679..11232835
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063999.7 → NP_496400.3  UVR domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496400.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22249
      Conserved Domains (2) summary
      COG0556
      Location:168 → 242
      UvrB; Excinuclease UvrABC helicase subunit UvrB [Replication, recombination and repair]
      pfam02151
      Location:204 → 237
      UVR; UvrB/uvrC motif
    Nucleotide Protein
    Heading Accession and Version

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