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    NCSTN nicastrin [ Gallus gallus (chicken) ]

    Gene ID: 426905, updated on 17-Aug-2024

    Summary

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    Symbol
    NCSTNprovided by CGNC
    Full Name
    nicastrinprovided by CGNC
    Primary source
    CGNC:6959
    See related
    Ensembl:ENSGALG00010027703
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See NCSTN in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 25 NC_052556.1 (1246584..1257422, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 25 NC_052597.1 (1247767..1258637, complement)

    Chromosome 25 - NC_052556.1Genomic Context describing neighboring genes Neighboring gene VANGL planar cell polarity protein 2 Neighboring gene uncharacterized LOC107055095 Neighboring gene nescient helix-loop-helix 1 Neighboring gene coatomer protein complex subunit alpha Neighboring gene trichohyalin-like Neighboring gene S100 calcium binding protein A11 Neighboring gene uncharacterized LOC121107559

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The chick embryo appears as a natural model for research in beta-amyloid precursor protein processing. Carrodeguas JA, et al. Neuroscience, 2005. PMID 16039787
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in Notch receptor processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nicastrin
    Names
    membrane protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004413.3 → NP_001004413.3  nicastrin precursor

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000349
      UniProtKB/TrEMBL
      Q67BJ3
      Related
      ENSGALP00010041044.1, ENSGALT00010067140.1
      Conserved Domains (1) summary
      cd03881
      Location:62 → 662
      M28_Nicastrin; M28 Zn-peptidase nicastrin, a main component of gamma-secretase complex

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052556.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      1246584..1257422 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052597.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      1247767..1258637 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials