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    best-15 Bestrophin homolog 15 [ Caenorhabditis elegans ]

    Gene ID: 177975, updated on 9-Dec-2024

    Summary

    Official Symbol
    best-15
    Official Full Name
    Bestrophin homolog 15
    Primary source
    WormBase:WBGene00011258
    Locus tag
    CELE_R13.3
    See related
    AllianceGenome:WB:WBGene00011258
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Orthologous to human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See best-15 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    12
    Sequence:
    Chromosome: IV; NC_003282.8 (10829549..10832248, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Paired domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene DBH-like monooxygenase protein 1;SET domain-containing protein Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables chloride channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables chloride channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chloride transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of chloride channel complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Bestrophin homolog 15
    NP_502007.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10829549..10832248 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069606.9NP_502007.2  Bestrophin homolog 15 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502007.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21973
      Conserved Domains (1) summary
      pfam01062
      Location:8321
      Bestrophin; Bestrophin, RFP-TM, chloride channel