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    F55A11.4 EF-hand domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186276, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F55A11.4
    Official Full Name
    EF-hand domain-containing protein
    Primary source
    WormBase:WBGene00010077
    Locus tag
    CELE_F55A11.4
    See related
    AllianceGenome:WB:WBGene00010077
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in transmembrane transport. Predicted to be located in mitochondrial inner membrane. Orthologous to several human genes including SLC25A25 (solute carrier family 25 member 25). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F55A11.4 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    9
    Sequence:
    Chromosome: V; NC_003283.11 (11770472..11773495)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Lysophosphatidylinositol acyltransferase 10 Neighboring gene GST C-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ADP transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ATP transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    EF-hand domain-containing protein
    NP_001256365.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      11770472..11773495
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269436.4 → NP_001256365.1  EF-hand domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256365.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20799
      UniProtKB/TrEMBL
      C8JQR9
      Conserved Domains (4) summary
      COG5126
      Location:70 → 211
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      cd00051
      Location:144 → 206
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam00153
      Location:248 → 337
      Mito_carr; Mitochondrial carrier protein
      cl08302
      Location:77 → 165
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    RNA

    1. NR_069619.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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