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    nhr-117 Nuclear Hormone Receptor family [ Caenorhabditis elegans ]

    Gene ID: 24104436, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nhr-117
    Official Full Name
    Nuclear Hormone Receptor family
    Primary source
    WormBase:WBGene00003707
    Locus tag
    CELE_F16B4.12
    See related
    AllianceGenome:WB:WBGene00003707
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in intestine and terminal bulb. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nhr-117 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (1619415..1621520, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class BC (Class B-like) Neighboring gene NR LBD domain-containing protein Neighboring gene NR LBD domain-containing protein;Nuclear receptor domain-containing protein Neighboring gene NR LBD domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ELT-2 GATA-factor and the global regulation of transcription in the C. elegans intestine. McGhee JD, et al. Dev Biol, 2007 Feb 15. PMID 17113066
    2. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nuclear Hormone Receptor family
    NP_001294718.1
    • Confirmed by transcript evidence
    NP_001294719.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      1619415..1621520 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001307789.5 → NP_001294718.1  Nuclear Hormone Receptor family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294718.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MNW2
      Conserved Domains (2) summary
      smart00399
      Location:33 → 103
      ZnF_C4; c4 zinc finger in nuclear hormone receptors
      pfam00104
      Location:206 → 411
      Hormone_recep; Ligand-binding domain of nuclear hormone receptor

    2. NM_001307790.4 → NP_001294719.1  Nuclear Hormone Receptor family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294719.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44638
      Conserved Domains (2) summary
      smart00399
      Location:33 → 103
      ZnF_C4; c4 zinc finger in nuclear hormone receptors
      pfam00104
      Location:248 → 453
      Hormone_recep; Ligand-binding domain of nuclear hormone receptor

    RNA

    1. NR_132511.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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    Molecular Biology Databases
    Research Materials