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    Pold4 DNA polymerase delta 4, accessory subunit [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361698, updated on 9-Dec-2024

    Summary

    Official Symbol
    Pold4provided by RGD
    Official Full Name
    DNA polymerase delta 4, accessory subunitprovided by RGD
    Primary source
    RGD:1308519
    See related
    EnsemblRapid:ENSRNOG00000018765 AllianceGenome:RGD:1308519
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to contribute to DNA-directed DNA polymerase activity. Involved in DNA-templated DNA replication. Predicted to be located in nucleus. Predicted to be part of delta DNA polymerase complex. Orthologous to human POLD4 (DNA polymerase delta 4, accessory subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 128.3), Liver (RPKM 123.0) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Pold4 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (210956110..210957863)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (201526591..201528406)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (219480841..219483244)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1 catalytic subunit alpha Neighboring gene RAD9 checkpoint clamp component A Neighboring gene cardiotrophin-like cytokine factor 1 Neighboring gene uncharacterized LOC103691274 Neighboring gene slingshot protein phosphatase 3

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    contributes_to DNA-directed DNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in DNA synthesis involved in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in DNA-templated DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in DNA-templated DNA replication IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in DNA-templated DNA replication ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of endothelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of delta DNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of delta DNA polymerase complex IC
    Inferred by Curator
    more info
    PubMed 
    part_of delta DNA polymerase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    DNA polymerase delta subunit 4
    Names
    DNA-directed DNA polymerase delta 4
    polymerase (DNA) delta 4, accessory subunit
    polymerase (DNA-directed), delta 4, accessory subunit

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013195.1NP_001013213.1  DNA polymerase delta subunit 4

      See identical proteins and their annotated locations for NP_001013213.1

      Status: PROVISIONAL

      Source sequence(s)
      BC062014
      UniProtKB/TrEMBL
      A6HYW0, F7F6Q0, Q6P6U6
      Related
      ENSRNOP00000025507.4, ENSRNOT00000025507.6
      Conserved Domains (1) summary
      pfam04081
      Location:4990
      DNA_pol_delta_4; DNA polymerase delta, subunit 4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      210956110..210957863
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006230841.5XP_006230903.1  DNA polymerase delta subunit 4 isoform X1

      See identical proteins and their annotated locations for XP_006230903.1

      UniProtKB/TrEMBL
      A6HYW0, A6HYW1
      Conserved Domains (1) summary
      pfam04081
      Location:4990
      DNA_pol_delta_4; DNA polymerase delta, subunit 4