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    ATP binding/leucine-tRNA ligases/aminoacyl-tRNA ligase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837489, updated on 18-Sep-2024

    Summary

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    Official Full Name
    ATP binding/leucine-tRNA ligases/aminoacyl-tRNA ligase
    Primary source
    TAIR:AT1G09620
    Locus tag
    AT1G09620
    See related
    Araport:AT1G09620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F21M12.1; F21M12_1
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (3112778..3116699, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene ncRNA Neighboring gene glucuronoxylan 4-O-methyltransferase-like protein (DUF579) Neighboring gene uncharacterized protein Neighboring gene RAB GTPase 11C Neighboring gene Translation elongation factor EF1B, gamma chain

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway. Iñigo S, et al. Plant Physiol, 2016 Oct. PMID 27503603, Free PMC Article
    2. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
    3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_100834.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables leucine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in leucyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    ATP binding/leucine-tRNA ligases/aminoacyl-tRNA ligase
    NP_172433.2
    • ATP binding;leucine-tRNA ligases;aminoacyl-tRNA ligases;nucleotide binding;ATP binding;aminoacyl-tRNA ligases; FUNCTIONS IN: nucleotide binding, aminoacyl-tRNA ligase activity, leucine-tRNA ligase activity, ATP binding; INVOLVED IN: leucyl-tRNA aminoacylation, translation, tRNA aminoacylation for protein translation; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aminoacyl-tRNA synthetase, class I, conserved site (InterPro:IPR001412), Aminoacyl-tRNA synthetase, class 1a, anticodon-binding (InterPro:IPR009080), Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding (InterPro:IPR013155), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing (InterPro:IPR009008), Aminoacyl-tRNA synthetase, class Ia (InterPro:IPR002300), Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic (InterPro:IPR004493); BEST Arabidopsis thaliana protein match is: tRNA synthetase class I (I, L, M and V) family protein (TAIR:AT4G04350.1); Has 16931 Blast hits to 15894 proteins in 2953 species: Archae - 757; Bacteria - 11010; Metazoa - 639; Fungi - 488; Plants - 264; Viruses - 0; Other Eukaryotes - 3773 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3112778..3116699 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100834.5 → NP_172433.2  ATP binding/leucine-tRNA ligases/aminoacyl-tRNA ligase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172433.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I116, Q56WB9
      UniProtKB/TrEMBL
      A0A5S9TGV8, A0A654EA84
      Conserved Domains (4) summary
      cd07959
      Location:754 → 874
      Anticodon_Ia_Leu_AEc; Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases
      cd00812
      Location:528 → 756
      LeuRS_core; catalytic core domain of leucyl-tRNA synthetases
      PLN02959
      Location:1 → 1082
      PLN02959; aminoacyl-tRNA ligase
      cl00015
      Location:45 → 207
      nt_trans; nucleotidyl transferase superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4I116.1

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