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    ALE1 PA-domain containing subtilase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842532, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ALE1
    Official Full Name
    PA-domain containing subtilase family protein
    Primary source
    TAIR:AT1G62340
    Locus tag
    AT1G62340
    See related
    Araport:AT1G62340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ABNORMAL LEAF-SHAPE; ABNORMAL LEAF-SHAPE 1; ALE; F24O1.36; F24O1_36
    Summary
    Subtilisin-like serine protease required for epidermal surface formation in embryos and juvenile plants
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    Genomic context

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    See ALE1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (23051002..23055672, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene O-fucosyltransferase family protein Neighboring gene uncharacterized protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene ncRNA Neighboring gene KNOX/ELK homeobox transcription factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A subtilisin-like serine protease is required for epidermal surface formation in Arabidopsis embryos and juvenile plants. Tanaka H, et al. Development, 2001 Dec. PMID 11731449
    2. "What we've got here is failure to communicate": zou mutants and endosperm cell death in seed development. Waters A, et al. Plant Signal Behav, 2013 Jun. PMID 23531691, Free PMC Article
    3. ZHOUPI controls embryonic cuticle formation via a signalling pathway involving the subtilisin protease ABNORMAL LEAF-SHAPE1 and the receptor kinases GASSHO1 and GASSHO2. Xing Q, et al. Development, 2013 Feb. PMID 23318634
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ZHOUPI regulates embryonic surface formation via a signaling pathway mediated by ABNORMAL LEAF SHAPE1.
      Title: "What we've got here is failure to communicate": zou mutants and endosperm cell death in seed development.
    2. ZHOUPI and ABNORMAL LEAF-SHAPE1 promote formation of embryonic cuticle via a pathway involving embryonically expressed receptor kinases GASSHO1 and GASSHO2.
      Title: ZHOUPI controls embryonic cuticle formation via a signalling pathway involving the subtilisin protease ABNORMAL LEAF-SHAPE1 and the receptor kinases GASSHO1 and GASSHO2.
    Submit: New GeneRIF Correction

    General gene information

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    NM_104914.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within plant epidermis development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    PA-domain containing subtilase family protein
    NP_564793.2
    • ABNORMAL LEAF-SHAPE 1 (ALE1); FUNCTIONS IN: serine-type endopeptidase activity; INVOLVED IN: proteolysis, cuticle development; LOCATED IN: endomembrane system, cell wall, membrane; EXPRESSED IN: embryo, endosperm; CONTAINS InterPro DOMAIN/s: Protease-associated PA (InterPro:IPR003137), Peptidase S8A, DUF1034 C-terminal (InterPro:IPR010435), Peptidase S8/S53, subtilisin/kexin/sedolisin (InterPro:IPR000209), Peptidase S8/S53, subtilisin, active site (InterPro:IPR022398), Proteinase inhibitor I9, subtilisin propeptide (InterPro:IPR010259), Peptidase S8, subtilisin-related (InterPro:IPR015500); BEST Arabidopsis thaliana protein match is: subtilisin-like serine protease 3 (TAIR:AT2G19170.1); Has 6975 Blast hits to 6033 proteins in 1018 species: Archae - 173; Bacteria - 4150; Metazoa - 21; Fungi - 269; Plants - 1839; Viruses - 0; Other Eukaryotes - 523 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23051002..23055672 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104914.2 → NP_564793.2  PA-domain containing subtilase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564793.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4HYR6, O48798, Q948Q4
      UniProtKB/TrEMBL
      A0A5S9WRT7, A0A654EKQ8
      Conserved Domains (3) summary
      cd04852
      Location:135 → 652
      Peptidases_S8_3; Peptidase S8 family domain, uncharacterized subfamily 3
      cd02120
      Location:389 → 533
      PA_subtilisin_like; PA_subtilisin_like: Protease-associated domain containing subtilisin-like proteases. This group contains various PA domain-containing subtilisin-like proteases including melon cucumisin, Arabidopsis thaliana Ara12, a nodule specific serine protease from ...
      pfam05922
      Location:70 → 138
      Inhibitor_I9; Peptidase inhibitor I9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4HYR6.1

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