MYB2 myb domain protein 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: MYB2
Official Full Name: myb domain protein 2
Primary source: TAIR:AT2G47190
Locus tag: AT2G47190
See related: Araport:AT2G47190
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATMYB2; myb domain protein 2; MYB DOMAIN PROTEIN 2; T8I13.3
Summary: Encodes a MYB transcription factor that possesses an R2R3 MYB DNA binding domain and is known to regulate the expression of salt- and dehydration-responsive genes. Has been shown to bind calmodulin.
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Genomic context

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See MYB2 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 3

Sequence:: Chromosome: 2; NC_003071.7 (19375985..19377543)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MYB2 Is Important for Tapetal PCD and Pollen Development by Directly Activating Protease Expression in Arabidopsis.
Title: MYB2 Is Important for Tapetal PCD and Pollen Development by Directly Activating Protease Expression in Arabidopsis.
The AtMYB2 inhibits the formation of axillary meristem in Arabidopsis by repressing RAX1 gene under environmental stresses.
Title: The AtMYB2 inhibits the formation of axillary meristem in Arabidopsis by repressing RAX1 gene under environmental stresses.
AtMYB2 regulates plant responses to phosphate starvation by regulating the expression of the miR399 gene.
Title: Regulation of miR399f transcription by AtMYB2 affects phosphate starvation responses in Arabidopsis.
The AtMYB2 transcription factor can therefore interact with the choline monooxygenase promoter directly and regulate its downstream gene expression.
Title: AtMYB2 transcription factor can interact with the CMO promoter and regulate its downstream gene expression.
An AtMYB2-regulated post apical dominance mechanism by which Arabidopsis (Arabidopsis thaliana) inhibits the outgrowth of axillary buds as part of the whole plant senescence program, is reported.
Title: AtMYB2 regulates whole plant senescence by inhibiting cytokinin-mediated branching at late stages of development in Arabidopsis.
Results demonstrate that the DNA-binding domain of AtMYB2 is inhibited by S-nitrosylation of Cys53 as a consequence of nitric oxide action.
Title: Inhibition of AtMYB2 DNA-binding by nitric oxide involves cysteine S-nitrosylation.
a specific CaM isoform mediates salt-induced Ca2+ signaling through the activation of an MYB transcriptional activator, thereby resulting in salt tolerance in plants.
Title: Direct interaction of a divergent CaM isoform and the transcription factor, MYB2, enhances salt tolerance in arabidopsis.
MYB2 is involved in iron translocation from roots to shoots.
Title: Transgenic expression of DwMYB2 impairs iron transport from root to shoot in Arabidopsis thaliana.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_130287.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables calmodulin binding	IDA Inferred from Direct Assay more info	PubMed
enables transcription cis-regulatory region binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular response to phosphate starvation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within response to abscisic acid	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to abscisic acid	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to salt stress	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to water deprivation	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	HDA more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: myb domain protein 2

NP_182241.1

myb domain protein 2 (MYB2); FUNCTIONS IN: calmodulin binding, DNA binding, transcription activator activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 112 (TAIR:AT1G48000.1); Has 8762 Blast hits to 8122 proteins in 475 species: Archae - 0; Bacteria - 0; Metazoa - 719; Fungi - 467; Plants - 5817; Viruses - 4; Other Eukaryotes - 1755 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

19375985..19377543

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_130287.3 → NP_182241.1 myb domain protein 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_182241.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178VX63, Q39028, Q93VZ0

Conserved Domains (2) summary

PLN03212
Location:20 → 123

PLN03212; Transcription repressor MYB5; Provisional

COG3061
Location:143 → 209

OapA; Cell envelope opacity-associated protein A (function unknown) [Function unknown]