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    ABCA1 ATP-binding cassette A1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818768, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ABCA1
    Official Full Name
    ATP-binding cassette A1
    Primary source
    TAIR:AT2G41700
    Locus tag
    AT2G41700
    See related
    Araport:AT2G41700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana ATP-binding cassette A1; AtABCA1; ATP-binding cassette A1
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    Genomic context

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    See ABCA1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    43
    Sequence:
    Chromosome: 2; NC_003071.7 (17382890..17396301, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene NADPH-dependent thioredoxin reductase C Neighboring gene heat shock transcription factor B3 Neighboring gene camphor resistance CrcB family protein Neighboring gene ncRNA Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Jaquinod M, et al. Mol Cell Proteomics, 2007 Mar. PMID 17151019, Free PMC Article
    2. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036449.1
    NM_180023.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    ATP-binding cassette A1
    NP_001031526.1
    • ATP-binding cassette A1 (ABCA1); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances, amino acid transmembrane transporter activity; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: ATP-binding cassette A2 (TAIR:AT3G47730.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_850354.2
    • ATP-binding cassette A1 (ABCA1); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances, amino acid transmembrane transporter activity; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: ATP-binding cassette A2 (TAIR:AT3G47730.1); Has 809471 Blast hits to 378826 proteins in 4091 species: Archae - 14583; Bacteria - 641508; Metazoa - 16186; Fungi - 10844; Plants - 9650; Viruses - 55; Other Eukaryotes - 116645 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17382890..17396301 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001036449.1 → NP_001031526.1  ATP-binding cassette A1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031526.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654FBK5, F4IKZ5
      Conserved Domains (4) summary
      TIGR01188
      Location:486 → 794
      drrA; daunorubicin resistance ABC transporter ATP-binding subunit
      cd03263
      Location:1411 → 1637
      ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
      COG1122
      Location:1408 → 1634
      EcfA2; Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only]
      pfam12698
      Location:1040 → 1265
      ABC2_membrane_3; ABC-2 family transporter protein

    2. NM_180023.4 → NP_850354.2  ATP-binding cassette A1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850354.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q2V410, Q84M24, Q8S8T6, Q8W010, Q941E2, Q9SDB1
      UniProtKB/TrEMBL
      A0A5S9X661
      Conserved Domains (5) summary
      TIGR01188
      Location:556 → 874
      drrA; daunorubicin resistance ABC transporter ATP-binding subunit
      cd03263
      Location:1453 → 1679
      ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
      COG1122
      Location:1450 → 1676
      EcfA2; Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only]
      pfam12698
      Location:1118 → 1381
      ABC2_membrane_3; ABC-2 family transporter protein
      cl14876
      Location:1215 → 1382
      Zinc_peptidase_like; Zinc peptidases M18, M20, M28, and M42
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84M24.2

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