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    3-oxo-5-alpha-steroid 4-dehydrogenase (DUF1295) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843699, updated on 18-Sep-2024

    Summary

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    Official Full Name
    3-oxo-5-alpha-steroid 4-dehydrogenase (DUF1295)
    Primary source
    TAIR:AT1G73650
    Locus tag
    AT1G73650
    See related
    Araport:AT1G73650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F25P22.7; F25P22_7
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (27688123..27690307, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Pathogenesis-related thaumatin superfamily protein Neighboring gene EF hand calcium-binding protein family Neighboring gene RAB GTPase homolog A6A Neighboring gene pseudo Neighboring gene FKBP-like peptidyl-prolyl cis-trans isomerase family protein Neighboring gene protein tyrosine kinase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130
    2. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article
    3. A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Jaquinod M, et al. Mol Cell Proteomics, 2007 Mar. PMID 17151019, Free PMC Article
    4. Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. Bellati J, et al. Mol Cell Proteomics, 2016 Nov. PMID 27609422, Free PMC Article
    5. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001124126.1
    NM_001334598.1
    NM_106023.3
    NM_179551.2
    NM_202411.1

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    3-oxo-5-alpha-steroid 4-dehydrogenase (DUF1295)
    NP_001117598.1
    • FUNCTIONS IN: oxidoreductase activity, acting on the CH-CH group of donors; INVOLVED IN: lipid metabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal (InterPro:IPR001104), Protein of unknown function DUF1295 (InterPro:IPR010721); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1295) (TAIR:AT1G18180.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_565068.1
    • FUNCTIONS IN: oxidoreductase activity, acting on the CH-CH group of donors; INVOLVED IN: lipid metabolic process; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal (InterPro:IPR001104), Protein of unknown function DUF1295 (InterPro:IPR010721); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1295) (TAIR:AT1G18180.1); Has 2028 Blast hits to 2028 proteins in 336 species: Archae - 0; Bacteria - 496; Metazoa - 80; Fungi - 120; Plants - 113; Viruses - 0; Other Eukaryotes - 1219 (source: NCBI BLink).
    NP_849882.2
    • FUNCTIONS IN: oxidoreductase activity, acting on the CH-CH group of donors; INVOLVED IN: lipid metabolic process; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal (InterPro:IPR001104), Protein of unknown function DUF1295 (InterPro:IPR010721); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1295) (TAIR:AT1G18180.1); Has 1888 Blast hits to 1888 proteins in 328 species: Archae - 0; Bacteria - 488; Metazoa - 78; Fungi - 114; Plants - 114; Viruses - 0; Other Eukaryotes - 1094 (source: NCBI BLink).
    NP_974140.1
    • FUNCTIONS IN: oxidoreductase activity, acting on the CH-CH group of donors; INVOLVED IN: lipid metabolic process; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal (InterPro:IPR001104), Protein of unknown function DUF1295 (InterPro:IPR010721); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1295) (TAIR:AT1G18180.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27688123..27690307 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202411.1 → NP_974140.1  3-oxo-5-alpha-steroid 4-dehydrogenase (DUF1295) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974140.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W5X3, F4HRY1
      Conserved Domains (1) summary
      pfam06966
      Location:24 → 252
      DUF1295; Protein of unknown function (DUF1295)

    2. NM_001334598.1 → NP_001323209.1  3-oxo-5-alpha-steroid 4-dehydrogenase (DUF1295) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W5X3, Q940M8
      Conserved Domains (1) summary
      pfam06966
      Location:24 → 252
      DUF1295; Protein of unknown function (DUF1295)

    3. NM_106023.3 → NP_565068.1  3-oxo-5-alpha-steroid 4-dehydrogenase (DUF1295) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565068.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W1Y5, A0A654ENR0, B9DFE9
      Conserved Domains (1) summary
      pfam06966
      Location:24 → 252
      DUF1295; Protein of unknown function (DUF1295)

    4. NM_179551.2 → NP_849882.2  3-oxo-5-alpha-steroid 4-dehydrogenase (DUF1295) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849882.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8MQG9
      Conserved Domains (1) summary
      cl21511
      Location:1 → 170
      PEMT; Phospholipid methyltransferase

    5. NM_001124126.1 → NP_001117598.1  3-oxo-5-alpha-steroid 4-dehydrogenase (DUF1295) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117598.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3H655
      Conserved Domains (1) summary
      cl21511
      Location:1 → 170
      PEMT; Phospholipid methyltransferase
    Nucleotide Protein
    Heading Accession and Version

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