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    ALPHA DOX2 alpha dioxygenase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843703, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ALPHA DOX2
    Official Full Name
    alpha dioxygenase
    Primary source
    TAIR:AT1G73680
    Locus tag
    AT1G73680
    See related
    Araport:AT1G73680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    alpha dioxygenase; alpha-dioxygenase 2; alpha-DOX2; F25P22.10; F25P22_10
    Summary
    Encodes an alpha dioxygenase. Recombinant protein catalyzes the conversion of a wide range of fatty acids into 2(R)-hydroperoxy derivatives.
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    Genomic context

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    See ALPHA DOX2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (27703944..27707657, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene protein tyrosine kinase family protein Neighboring gene MAP kinase 15 Neighboring gene miscRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of alpha-DOX2, an active alpha-dioxygenase critical for normal development in tomato plants. Bannenberg G, et al. Plant Physiol, 2009 Nov. PMID 19759339, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001198464.1
    NM_001334599.1
    NM_001334600.1
    NM_106027.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within fatty acid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf senescence IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within long-chain fatty acid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    alpha dioxygenase
    NP_001185393.1
    • alpha dioxygenase (ALPHA DOX2); CONTAINS InterPro DOMAIN/s: Haem peroxidase (InterPro:IPR010255), Haem peroxidase, animal (InterPro:IPR002007); BEST Arabidopsis thaliana protein match is: Peroxidase superfamily protein (TAIR:AT3G01420.1).
    NP_177509.1
    • alpha dioxygenase (ALPHA DOX2); CONTAINS InterPro DOMAIN/s: Haem peroxidase (InterPro:IPR010255), Haem peroxidase, animal (InterPro:IPR002007); BEST Arabidopsis thaliana protein match is: Peroxidase superfamily protein (TAIR:AT3G01420.1); Has 1634 Blast hits to 1495 proteins in 223 species: Archae - 0; Bacteria - 102; Metazoa - 1237; Fungi - 165; Plants - 68; Viruses - 3; Other Eukaryotes - 59 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27703944..27707657 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106027.3 → NP_177509.1  alpha dioxygenase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177509.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4HRY9, Q9C9U3
      UniProtKB/TrEMBL
      A0A5S9WU40
      Conserved Domains (2) summary
      PLN02283
      Location:1 → 631
      PLN02283; alpha-dioxygenase
      pfam03098
      Location:84 → 600
      An_peroxidase; Animal haem peroxidase

    2. NM_001334599.1 → NP_001322743.1  alpha dioxygenase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AUY0, A0A7G2E614

    3. NM_001334600.1 → NP_001322742.1  alpha dioxygenase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AV22

    4. NM_001198464.1 → NP_001185393.1  alpha dioxygenase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185393.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9WU40
      Conserved Domains (2) summary
      PLN02283
      Location:1 → 640
      PLN02283; alpha-dioxygenase
      pfam03098
      Location:84 → 609
      An_peroxidase; Animal haem peroxidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C9U3.1

    Gene LinkOut

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