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    SAHH2 S-adenosyl-l-homocysteine (SAH) hydrolase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821964, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SAHH2
    Official Full Name
    S-adenosyl-l-homocysteine (SAH) hydrolase 2
    Primary source
    TAIR:AT3G23810
    Locus tag
    AT3G23810
    See related
    Araport:AT3G23810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSAHH2; S-adenosyl-l-homocysteine (SAH) hydrolase 2; S-ADENOSYL-L-HOMOCYSTEINE (SAH) HYDROLASE 2
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    Genomic context

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    See SAHH2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (8587622..8589754, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene selenium-binding protein 3 Neighboring gene ralf-like 24 Neighboring gene ncRNA Neighboring gene UDP-D-glucuronate 4-epimerase 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana. Shimaoka T, et al. Plant Cell Physiol, 2004 Jun. PMID 15215502
    2. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_113286.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    S-adenosyl-l-homocysteine (SAH) hydrolase 2
    NP_189023.1
    • S-adenosyl-l-homocysteine (SAH) hydrolase 2 (SAHH2); FUNCTIONS IN: adenosylhomocysteinase activity; INVOLVED IN: one-carbon metabolic process; LOCATED IN: plasma membrane, vacuole, membrane; EXPRESSED IN: 33 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: S-adenosyl-L-homocysteine hydrolase (InterPro:IPR000043), S-adenosyl-L-homocysteine hydrolase, conserved site (InterPro:IPR020082), S-adenosyl-L-homocysteine hydrolase, NAD binding (InterPro:IPR015878); BEST Arabidopsis thaliana protein match is: S-adenosyl-L-homocysteine hydrolase (TAIR:AT4G13940.1); Has 7939 Blast hits to 7933 proteins in 1466 species: Archae - 229; Bacteria - 2315; Metazoa - 640; Fungi - 145; Plants - 247; Viruses - 0; Other Eukaryotes - 4363 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      8587622..8589754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113286.3 → NP_189023.1  S-adenosyl-l-homocysteine (SAH) hydrolase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189023.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LPS8, Q944K5, Q949Z9, Q9LK36
      UniProtKB/TrEMBL
      A0A178VEP9, A0A5S9XFK3, A7XB43, Q5D6C3, Q5D6C4, Q5D6C5
      Conserved Domains (1) summary
      PLN02494
      Location:9 → 485
      PLN02494; adenosylhomocysteinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LK36.1

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