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    dihydrofolate reductase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828540, updated on 18-Sep-2024

    Summary

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    Official Full Name
    dihydrofolate reductase
    Primary source
    TAIR:AT4G24380
    Locus tag
    AT4G24380
    See related
    Araport:AT4G24380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T22A6.210; T22A6_210
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (12612378..12613719)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Phosphorylase superfamily protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene RNI-like superfamily protein Neighboring gene CBL-interacting protein kinase 8 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001036630.3
    NM_001341665.1
    NM_001341666.1
    NM_001341667.1
    NM_001341668.1
    NM_118571.5

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    dihydrofolate reductase
    NP_001031707.1
    • CONTAINS InterPro DOMAIN/s: Serine hydrolase (InterPro:IPR005645); BEST Arabidopsis thaliana protein match is: alpha/beta-Hydrolases superfamily protein (TAIR:AT5G65400.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_567701.1
    • INVOLVED IN: 10-formyltetrahydrofolate biosynthetic process, folic acid and derivative biosynthetic process; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Serine hydrolase (InterPro:IPR005645); BEST Arabidopsis thaliana protein match is: alpha/beta-Hydrolases superfamily protein (TAIR:AT5G65400.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12612378..12613719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118571.5 → NP_567701.1  dihydrofolate reductase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567701.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UZG5, A0A654FSG9, Q8GX45, Q8LC87
      Conserved Domains (1) summary
      pfam03959
      Location:10 → 201
      FSH1; Serine hydrolase (FSH1)

    2. NM_001036630.3 → NP_001031707.1  dihydrofolate reductase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031707.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JQW1
      Conserved Domains (1) summary
      cl21494
      Location:10 → 166
      Abhydrolase; alpha/beta hydrolases

    3. NM_001341665.1 → NP_001329756.1  dihydrofolate reductase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B8P6, A0A654FSG9, Q8LC87

    4. NM_001341666.1 → NP_001329755.1  dihydrofolate reductase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B8Q2

    5. NM_001341667.1 → NP_001329754.1  dihydrofolate reductase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B8P1

    6. NM_001341668.1 → NP_001329753.1  dihydrofolate reductase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B8P4
    Nucleotide Protein
    Heading Accession and Version

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