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    C2 domain-containing protein / GRAM domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825135, updated on 18-Sep-2024

    Summary

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    Official Full Name
    C2 domain-containing protein / GRAM domain-containing protein
    Primary source
    TAIR:AT3G59660
    Locus tag
    AT3G59660
    See related
    Araport:AT3G59660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    18
    Sequence:
    Chromosome: 3; NC_003074.8 (22034171..22038709, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene diphthamide synthesis DPH2 family protein Neighboring gene glycine-rich protein Neighboring gene mitochondrial ribosomal protein L51/S25/CI-B8 family protein Neighboring gene elongation factor Neighboring gene Serine/Threonine-kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Aspartyl Protease-Mediated Cleavage of BAG6 Is Necessary for Autophagy and Fungal Resistance in Plants. Li Y, et al. Plant Cell, 2016 Jan. PMID 26739014, Free PMC Article
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001339993.1
    NM_115828.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    acts_upstream_of_or_within defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    C2 domain-containing protein / GRAM domain-containing protein
    NP_191525.2
    • C2 domain-containing protein / GRAM domain-containing protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), GRAM (InterPro:IPR004182), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: C2 calcium/lipid-binding and GRAM domain containing protein (TAIR:AT1G03370.1); Has 2988 Blast hits to 2683 proteins in 223 species: Archae - 0; Bacteria - 0; Metazoa - 1633; Fungi - 370; Plants - 725; Viruses - 0; Other Eukaryotes - 260 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      22034171..22038709 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115828.5 → NP_191525.2  C2 domain-containing protein / GRAM domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191525.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W4D4, Q9M1A2
      UniProtKB/TrEMBL
      A0A178VKU9, A0A5S9XMA9
      Conserved Domains (3) summary
      cd00030
      Location:83 → 179
      C2; C2 domain
      cd13219
      Location:240 → 348
      PH-GRAM_C2-GRAM; C2 and GRAM domain-containing protein Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam16016
      Location:406 → 552
      DUF4782; Domain of unknown function (DUF4782)

    2. NM_001339993.1 → NP_001326264.1  C2 domain-containing protein / GRAM domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LNR1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8W4D4.1

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