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    EMB1241 Co-chaperone GrpE family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831638, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EMB1241
    Official Full Name
    Co-chaperone GrpE family protein
    Primary source
    TAIR:AT5G17710
    Locus tag
    AT5G17710
    See related
    Araport:AT5G17710
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    embryo defective 1241; MVA3.60; MVA3_60
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    Genomic context

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    See EMB1241 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (5839163..5841858, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene MATE efflux family protein Neighboring gene ncRNA Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two Arabidopsis Chloroplast GrpE Homologues Exhibit Distinct Biological Activities and Can Form Homo- and Hetero-Oligomers. Su PH, et al. Front Plant Sci, 2019. PMID 32038688, Free PMC Article
    2. Functional analysis of the Chloroplast GrpE (CGE) proteins from Arabidopsis thaliana. de Luna-Valdez LA, et al. Plant Physiol Biochem, 2019 Jun. PMID 30927692
    3. High light response of the thylakoid proteome in arabidopsis wild type and the ascorbate-deficient mutant vtc2-2. A comparative proteomics study. Giacomelli L, et al. Plant Physiol, 2006 Jun. PMID 16648217, Free PMC Article
    4. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article
    5. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001343522.1
    NM_121777.3
    NM_180509.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables adenyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables copper ion binding HDA PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-folding chaperone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to heat IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within protein folding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein stabilization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 
    located_in thylakoid HDA PubMed 

    General protein information

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    Preferred Names
    Co-chaperone GrpE family protein
    NP_001318588.1
    • embryo defective 1241 (EMB1241); FUNCTIONS IN: copper ion binding; INVOLVED IN: protein folding, embryo development ending in seed dormancy; LOCATED IN: thylakoid, chloroplast, chloroplast stroma; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: GrpE nucleotide exchange factor (InterPro:IPR000740), GrpE nucleotide exchange factor, coiled-coil (InterPro:IPR013805), GrpE nucleotide exchange factor, head (InterPro:IPR009012); BEST Arabidopsis thaliana protein match is: Co-chaperone GrpE family protein (TAIR:AT1G36390.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_850840.1
    • embryo defective 1241 (EMB1241); FUNCTIONS IN: copper ion binding; INVOLVED IN: protein folding, embryo development ending in seed dormancy; LOCATED IN: thylakoid, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: GrpE nucleotide exchange factor (InterPro:IPR000740), GrpE nucleotide exchange factor, coiled-coil (InterPro:IPR013805), GrpE nucleotide exchange factor, head (InterPro:IPR009012); BEST Arabidopsis thaliana protein match is: Co-chaperone GrpE family protein (TAIR:AT1G36390.2); Has 8394 Blast hits to 8358 proteins in 2682 species: Archae - 138; Bacteria - 5138; Metazoa - 231; Fungi - 167; Plants - 159; Viruses - 7; Other Eukaryotes - 2554 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5839163..5841858 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343522.1 → NP_001318588.1  Co-chaperone GrpE family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y514, Q94K56

    2. NM_180509.4 → NP_850840.1  Co-chaperone GrpE family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850840.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178U8H4, A0A5S9Y514, Q9FN80, Q9XQC7
      Conserved Domains (2) summary
      cd00446
      Location:163 → 210
      GrpE; 2-helical coiled coil [structural motif]
      cl03075
      Location:154 → 316
      GrpE; nucleotide exchange factor GrpE

    3. NM_121777.3 → NP_568356.1  Co-chaperone GrpE family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568356.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y514, Q94K56
      Conserved Domains (2) summary
      cd00446
      Location:161 → 208
      GrpE; 2-helical coiled coil [structural motif]
      cl03075
      Location:152 → 314
      GrpE; nucleotide exchange factor GrpE
    Nucleotide Protein
    Heading Accession and Version

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