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    GAF1 Polymerase/histidinol phosphatase-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836120, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GAF1
    Official Full Name
    Polymerase/histidinol phosphatase-like protein
    Primary source
    TAIR:AT5G59980
    Locus tag
    AT5G59980
    See related
    Araport:AT5G59980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtRPP30; GAMETOPHYTE DEFECTIVE 1; MMN10.23; MMN10_23; RPP30
    Summary
    Encodes a predicted protein subunit of RNases P/MRP that plays a role in female gametophyte development and male competence.
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    Genomic context

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    See GAF1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (24147099..24149942)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene K-stimulated pyrophosphate-energized sodium pump protein Neighboring gene Histone superfamily protein Neighboring gene CCT motif family protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SCARECROW-LIKE3 regulates the transcription of gibberellin-related genes by acting as a transcriptional co-repressor of GAI-ASSOCIATED FACTOR1. Ito T, et al. Plant Mol Biol, 2021 Mar. PMID 33474657
    2. GAMETOPHYTE DEFECTIVE 1, a putative subunit of RNases P/MRP, is essential for female gametogenesis and male competence in Arabidopsis. Wang SQ, et al. PLoS One, 2012. PMID 22509260, Free PMC Article
    3. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Fukazawa J, et al. Plant Cell, 2014 Jul. PMID 25035403, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SCARECROW-LIKE3 regulates the transcription of gibberellin-related genes by acting as a transcriptional co-repressor of GAI-ASSOCIATED FACTOR1.
      Title: SCARECROW-LIKE3 regulates the transcription of gibberellin-related genes by acting as a transcriptional co-repressor of GAI-ASSOCIATED FACTOR1.
    2. Components of the RNases P/MRP family, such as RPP30, play important roles in gametophyte development and function in plants. [GAF1]
      Title: GAMETOPHYTE DEFECTIVE 1, a putative subunit of RNases P/MRP, is essential for female gametogenesis and male competence in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_001161317.2
    NM_001345380.1
    NM_001345381.1
    NM_125391.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo sac development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Polymerase/histidinol phosphatase-like protein
    NP_001154789.1
    • Polymerase/histidinol phosphatase-like; FUNCTIONS IN: tRNA-intron endonuclease activity, ribonuclease activity, catalytic activity; INVOLVED IN: tRNA processing; LOCATED IN: cellular_component unknown; EXPRESSED IN: trichome; CONTAINS InterPro DOMAIN/s: Polymerase/histidinol phosphatase-like (InterPro:IPR016195), RNase P subunit p30 (InterPro:IPR002738); Has 1908 Blast hits to 1535 proteins in 339 species: Archae - 16; Bacteria - 381; Metazoa - 491; Fungi - 307; Plants - 100; Viruses - 13; Other Eukaryotes - 600 (source: NCBI BLink).
    NP_200806.2
    • Polymerase/histidinol phosphatase-like; FUNCTIONS IN: tRNA-intron endonuclease activity, ribonuclease activity, catalytic activity; INVOLVED IN: tRNA processing; LOCATED IN: cellular_component unknown; EXPRESSED IN: trichome; CONTAINS InterPro DOMAIN/s: Polymerase/histidinol phosphatase-like (InterPro:IPR016195), RNase P subunit p30 (InterPro:IPR002738); Has 397 Blast hits to 397 proteins in 185 species: Archae - 13; Bacteria - 5; Metazoa - 139; Fungi - 139; Plants - 45; Viruses - 0; Other Eukaryotes - 56 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24147099..24149942
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001161317.2 → NP_001154789.1  Polymerase/histidinol phosphatase-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154789.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UP70, A0A5S9YGB1, F4JXF0
      Conserved Domains (1) summary
      pfam01876
      Location:4 → 248
      RNase_P_p30; RNase P subunit p30

    2. NM_125391.3 → NP_200806.2  Polymerase/histidinol phosphatase-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200806.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JXF1, Q9FJD9
      UniProtKB/TrEMBL
      A0A5S9YGB1
      Conserved Domains (1) summary
      pfam01876
      Location:4 → 247
      RNase_P_p30; RNase P subunit p30

    3. NM_001345380.1 → NP_001332678.1  Polymerase/histidinol phosphatase-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1R7T3D1, A0A5S9YGB1
      Conserved Domains (2) summary
      COG5271
      Location:524 → 639
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam01876
      Location:4 → 248
      RNase_P_p30; RNase P subunit p30

    4. NM_001345381.1 → NP_001332679.1  Polymerase/histidinol phosphatase-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1R7T3D2, A0A5S9YGB1, A0A654GCV9
      Conserved Domains (2) summary
      COG5271
      Location:524 → 650
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam01876
      Location:4 → 247
      RNase_P_p30; RNase P subunit p30
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4JXF1.1

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