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    ATGRIP Golgi-localized GRIP domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836733, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATGRIP
    Official Full Name
    Golgi-localized GRIP domain-containing protein
    Primary source
    TAIR:AT5G66030
    Locus tag
    AT5G66030
    See related
    Araport:AT5G66030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    GRIP; K2A18.10; K2A18_10
    Summary
    Involved in golgi protein trafficking. AtARL1 binds directly to the GRIP domain of AtGRIP in a GTP-dependent manner. Localized to the golgi apparatus, tyrosine 717 in AtGRIP is crucial for Golgi localization.
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    Genomic context

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    See ATGRIP in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    21
    Sequence:
    Chromosome: 5; NC_003076.8 (26404893..26410355, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein Neighboring gene Phosphoinositide phosphatase family protein Neighboring gene sulfurtransferase protein 16 Neighboring gene Wound-responsive family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The C-TERMINUS of AtGRIP is crucial for its self-association and for targeting to Golgi stacks in Arabidopsis. Zhao L, et al. PLoS One, 2014. PMID 24901770, Free PMC Article
    2. Identification of a Golgi-localised GRIP domain protein from Arabidopsis thaliana. Gilson PR, et al. Planta, 2004 Oct. PMID 15605178
    3. ARL1 plays a role in the binding of the GRIP domain of a peripheral matrix protein to the Golgi apparatus in plant cells. Stefano G, et al. Plant Mol Biol, 2006 Jun. PMID 16830178
    4. An Arabidopsis GRIP domain protein locates to the trans-Golgi and binds the small GTPase ARL1. Latijnhouwers M, et al. Plant J, 2005 Nov. PMID 16236155
    5. Fluorescence lifetime imaging of interactions between Golgi tethering factors and small GTPases in plants. Osterrieder A, et al. Traffic, 2009 Aug. PMID 19490533

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001345737.1
    NM_001345738.1
    NM_126000.2
    NM_180946.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within Golgi vesicle transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Golgi-localized GRIP domain-containing protein
    NP_569025.2
    • ATGRIP; CONTAINS InterPro DOMAIN/s: GRIP (InterPro:IPR000237); Has 226693 Blast hits to 107013 proteins in 3750 species: Archae - 2739; Bacteria - 54726; Metazoa - 91166; Fungi - 18242; Plants - 12768; Viruses - 908; Other Eukaryotes - 46144 (source: NCBI BLink).
    NP_851277.1
    • ATGRIP; CONTAINS InterPro DOMAIN/s: Prefoldin (InterPro:IPR009053), GRIP (InterPro:IPR000237); Has 226787 Blast hits to 107130 proteins in 3750 species: Archae - 2735; Bacteria - 54789; Metazoa - 91225; Fungi - 18234; Plants - 12767; Viruses - 906; Other Eukaryotes - 46131 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      26404893..26410355 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180946.3 → NP_851277.1  Golgi-localized GRIP domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851277.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3E854, Q8S2T0, Q944S6, Q9FKX9
      UniProtKB/TrEMBL
      A0A5S9YI67
      Conserved Domains (2) summary
      smart00755
      Location:712 → 755
      Grip; golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
      pfam07851
      Location:166 → 257
      TMPIT; TMPIT-like protein

    2. NM_001345737.1 → NP_001332639.1  Golgi-localized GRIP domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1R7T390, B9DFM0

    3. NM_001345738.1 → NP_001332640.1  Golgi-localized GRIP domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1R7T391, B9DFM0

    4. NM_126000.2 → NP_569025.2  Golgi-localized GRIP domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_569025.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9YI67
      Conserved Domains (2) summary
      pfam01465
      Location:713 → 750
      GRIP; GRIP domain
      pfam07851
      Location:166 → 257
      TMPIT; TMPIT-like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8S2T0.2

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