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    Fam131a family with sequence similarity 131, member A [ Mus musculus (house mouse) ]

    Gene ID: 78408, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fam131aprovided by MGI
    Official Full Name
    family with sequence similarity 131, member Aprovided by MGI
    Primary source
    MGI:MGI:1925658
    See related
    Ensembl:ENSMUSG00000050821 AllianceGenome:MGI:1925658
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2900046G09Rik
    Summary
    Is expressed in central nervous system and retina. Orthologous to human FAM131A (family with sequence similarity 131 member A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cortex adult (RPKM 51.7), frontal lobe adult (RPKM 40.8) and 12 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam131a in Genome Data Viewer
    Location:
    16 A3; 16 12.5 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (20511856..20521794)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (20693094..20703044)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation elongation factor 1 gamma pseudogene Neighboring gene eukaryotic translation initiation factor 4, gamma 1 Neighboring gene small nucleolar RNA, C/D box 66 Neighboring gene STARR-seq mESC enhancer starr_40329 Neighboring gene chloride channel, voltage-sensitive 2 Neighboring gene STARR-positive B cell enhancer ABC_E1489 Neighboring gene polymerase (RNA) II (DNA directed) polypeptide H Neighboring gene STARR-seq mESC enhancer starr_40331 Neighboring gene thrombopoietin Neighboring gene chordin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
    4. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1)  1 citation

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM131A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133778.2 → NP_598539.1  protein FAM131A

      See identical proteins and their annotated locations for NP_598539.1

      Status: PROVISIONAL

      Source sequence(s)
      AK049983
      Consensus CDS
      CCDS28056.1
      UniProtKB/Swiss-Prot
      Q8BWU3, Q99KY5
      Related
      ENSMUSP00000060194.7, ENSMUST00000056518.13
      Conserved Domains (1) summary
      pfam15010
      Location:86 → 356
      FAM131; Putative cell signalling

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      20511856..20521794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249332.2 → XP_030105192.1  protein FAM131A isoform X4

      Related
      ENSMUSP00000156118.2, ENSMUST00000232207.2
      Conserved Domains (1) summary
      pfam15010
      Location:1 → 133
      FAM131; Putative cell signalling

    2. XM_006522741.5 → XP_006522804.1  protein FAM131A isoform X3

      See identical proteins and their annotated locations for XP_006522804.1

      UniProtKB/TrEMBL
      D3Z4E4
      Conserved Domains (1) summary
      pfam15010
      Location:1 → 271
      FAM131; Putative cell signalling

    3. XM_006522740.5 → XP_006522803.1  protein FAM131A isoform X3

      See identical proteins and their annotated locations for XP_006522803.1

      UniProtKB/TrEMBL
      D3Z4E4
      Related
      ENSMUSP00000113719.2, ENSMUST00000118919.9
      Conserved Domains (1) summary
      pfam15010
      Location:1 → 271
      FAM131; Putative cell signalling

    4. XM_017317161.3 → XP_017172650.1  protein FAM131A isoform X2

      Conserved Domains (1) summary
      pfam15010
      Location:86 → 218
      FAM131; Putative cell signalling

    5. XM_006522738.5 → XP_006522801.1  protein FAM131A isoform X1

      Conserved Domains (1) summary
      pfam15010
      Location:77 → 347
      FAM131; Putative cell signalling

    6. XM_006522742.5 → XP_006522805.1  protein FAM131A isoform X3

      See identical proteins and their annotated locations for XP_006522805.1

      UniProtKB/TrEMBL
      D3Z4E4
      Conserved Domains (1) summary
      pfam15010
      Location:1 → 271
      FAM131; Putative cell signalling
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BWU3.1 GenPept UniProtKB/Swiss-Prot:Q8BWU3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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