pde6hb phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pde6hbprovided by ZNC
Official Full Name: phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1777
See related: AllianceGenome:ZFIN:ZDB-GENE-040426-1777
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:73359
Summary: Predicted to enable 3',5'-cyclic-GMP phosphodiesterase activity and cGMP binding activity. Predicted to act upstream of or within visual perception. Is expressed in spinal cord and visual system. [provided by Alliance of Genome Resources, Dec 2024]
Annotation information: Annotation category: partial on reference assembly
Orthologs: all
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Genomic context

Location:: chromosome: Un

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	Unplaced Scaffold	NW_003334236.1 (360..17627)
105	previous assembly	GRCz10 (GCF_000002035.5)	Unplaced Scaffold	NW_003334236.1 (360..17627)

NW_003334236.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 3',5'-cyclic-GMP phosphodiesterase activity	IEA Inferred from Electronic Annotation more info
enables 3',5'-cyclic-nucleotide phosphodiesterase activity	IEA Inferred from Electronic Annotation more info
enables cGMP binding	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of epidermal growth factor receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within visual perception	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
is_active_in photoreceptor outer segment membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

NP_957131.1

EC 3.1.4.35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200837.1 → NP_957131.1 retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

See identical proteins and their annotated locations for NP_957131.1

Status: PROVISIONAL

Source sequence(s)

BC060940

UniProtKB/TrEMBL

Q6P936

Conserved Domains (1) summary

pfam04868
Location:6 → 87

PDE6_gamma; Retinal cGMP phosphodiesterase, gamma subunit