nipsnap2 nipsnap homolog 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nipsnap2provided by ZNC
Official Full Name: nipsnap homolog 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-991008-18
See related: AllianceGenome:ZFIN:ZDB-GENE-991008-18
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: gbas; zgc:92497; wu:fc08b08
Summary: Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in mitophagy. Predicted to act upstream of or within autophagy. Predicted to be located in cytoplasm. Predicted to be active in mitochondrial matrix. Is expressed in brain; heart; myotome; ovary; and testis. Orthologous to human NIPSNAP2 (nipsnap homolog 2). [provided by Alliance of Genome Resources, Dec 2024]
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (404875..414036)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (494894..504604)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

NIPSNAP1 and NIPSNAP2 act as ""eat me"" signals to allow sustained recruitment of autophagy receptors during mitophagy.
Title: NIPSNAP1 and NIPSNAP2 act as "eat me" signals to allow sustained recruitment of autophagy receptors during mitophagy.
NIPSNAP1 and NIPSNAP2 have a redundant function in mitophagy and are predominantly expressed in different tissues.
Title: NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy.

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General gene information

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Markers

G47805 (e-PCR)
- UniSTS:108574

AI626393 (e-PCR)
- UniSTS:206136

fc08b08.y1 (e-PCR)
- UniSTS:192331

fb51h07.x1 (e-PCR)
- UniSTS:190660

G48017 (e-PCR)
- UniSTS:108782

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein-macromolecule adaptor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within autophagy	IEA Inferred from Electronic Annotation more info
involved_in mitophagy	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
is_active_in mitochondrial matrix	ISS Inferred from Sequence or Structural Similarity more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: protein NipSnap homolog 2

Names: glioblastoma amplified sequence

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.