phf6 PHD finger protein 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: phf6provided by ZNC
Official Full Name: PHD finger protein 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5278
See related: Ensembl:ENSDARG00000004046 AllianceGenome:ZFIN:ZDB-GENE-030131-5278
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:55403; wu:fa22g03
Summary: Predicted to enable histone binding activity and histone deacetylase binding activity. Acts upstream of or within regulation of T cell differentiation in thymus. Predicted to be active in nucleus. Is expressed in brain; eye; liver; pleuroperitoneal region; and thymus. Human ortholog(s) of this gene implicated in Borjeson-Forssman-Lehmann syndrome; acute myeloid leukemia; and congestive heart failure. Orthologous to human PHF6 (PHD finger protein 6). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 14

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (31493274..31507740)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (31152960..31167426)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fi29b03.x1 (e-PCR)
- UniSTS:197196

fa22g03.s1 (e-PCR)
- UniSTS:202479

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of T cell differentiation in thymus	IMP Inferred from Mutant Phenotype more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: PHD finger protein 6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199765.1 → NP_956059.1 PHD finger protein 6

See identical proteins and their annotated locations for NP_956059.1

Status: PROVISIONAL

Source sequence(s)

BC044163

UniProtKB/TrEMBL

A0A8M9QKI0, Q803W6

Related

ENSDARP00000023828.5, ENSDART00000006463.7

Conserved Domains (2) summary

cd15710
Location:15 → 129

ePHD1_PHF6; Extended PHD finger 1 found in PHD finger protein 6 (PHF6)

cd15711
Location:210 → 327

ePHD2_PHF6; Extended PHD finger 2 found in PHD finger protein 6 (PHF6)