mrpl45 mitochondrial ribosomal protein L45 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mrpl45provided by ZNC
Official Full Name: mitochondrial ribosomal protein L45provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1041
See related: Ensembl:ENSDARG00000044942 AllianceGenome:ZFIN:ZDB-GENE-040426-1041
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56480
Summary: Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Predicted to be active in mitochondrion. Orthologous to human MRPL45 (mitochondrial ribosomal protein L45). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (12096035..12104929, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (12112414..12121308, complement)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: large ribosomal subunit protein mL45

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001328585.1 → NP_001315514.1 large ribosomal subunit protein mL45 isoform 1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

Source sequence(s)

BX469912, EH546243, EH576059

UniProtKB/TrEMBL

A0A8M1PAH5, E9QEK4

Related

ENSDARP00000121834.1, ENSDART00000136108.3

Conserved Domains (1) summary

pfam04280
Location:125 → 272

Tim44; Tim44-like domain
NM_200307.2 → NP_956601.2 large ribosomal subunit protein mL45 isoform 2

Status: VALIDATED

Description

Transcript Variant: This variant (2) differs in the 5' UTR, and uses an alternate splice site in its 5' coding region resulting in a frameshift compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus compared to isoform 1.

Source sequence(s)

BX469912

UniProtKB/TrEMBL

A0A8M1PCS1