id3 inhibitor of DNA binding 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: id3provided by ZNC
Official Full Name: inhibitor of DNA binding 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-020515-1
See related: Ensembl:ENSDARG00000054823 AllianceGenome:ZFIN:ZDB-GENE-020515-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fa56g03; tdsubc_2g3; wu:fa56g03; ik:tdsubc_2g3; xx:tdsubc_2g3
Summary: Predicted to enable transcription corepressor activity. Acts upstream of or within dopaminergic neuron differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including digestive system; germ ring; nervous system; polster; and presumptive ectoderm. Orthologous to human ID3 (inhibitor of DNA binding 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 17

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (27271399..27273303, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (27253008..27254912, complement)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data revealed that expression of DNA binding inhibitor 3, early B cell factor 2, Ebf3, Iroquois related homeobox 1, Kruppel-like factor 7 , mab-21-like 1 , fatty acid binding protein 7 and stathmin-like 4,were enriched in the diencephalon of zebrafish.
Title: Expression of ventral diencephalon-enriched genes in zebrafish.
expression of id3 in zebrafish embryo
Title: Expression of the helix-loop-helix gene id3 in the zebrafish embryo.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info
enables transcription corepressor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within dopaminergic neuron differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within negative regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in neuron differentiation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: DNA-binding protein inhibitor ID-3

Names: Id2d; etID138038.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.